NEWS
FINDING LINKS PERIODS AND SOME DRUG-RESISTANT EPILEPSY
New research links more frequent seizures during the menstrual cycle of women with genetic generalized epilepsy with drug-resistant epilepsy, in which anti-seizure medications don’t work. The finding may help lead to tailored treatments. Women with a form of genetic...
Long-term brain monitoring technologies can benefit epilepsy patients
Today, the way a physician gets an idea of how many seizures a person with epilepsy has had is through the patient's own record of seizure activity in his day-to-day life. Despite all the technological advances in devices monitoring the human body, a patient's seizure...
Seizures during menstrual cycle linked to drug-resistant epilepsy
Study finds surprising connection in some women with genetic generalized epilepsy More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications...
DEA Proposes New Rule For Regulating Hemp-Derived CBD
The rule also establishes that the FDA-approved medications that include CBD, such as the epilepsy treatment Epidiolex, are to be removed from Schedule V of the Controlled Substances Act. The U.S. Drug Enforcement Administration on Thursday submitted a proposed rule...
Study focuses on genetic neurological disorders that develop in children over time.
A team of researchers at Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) further bridged the gap between genomic information and clinical outcome data by systematically linking genetic information with...
Early Blood Test Can Detect Baby Brain Damage Just Hours After Birth.
An early blood test could detect which babies deprived of oxygen at birth are at risk of serious neuro disabilities. Researchers, including one of Indian origin, have found that an early blood test could detect which babies deprived of oxygen at birth are at risk of...
Three Diets Cut Seizures in Kids with Intractable Epilepsy
Trial compares major ketogenic diet therapy methods Three major methods of providing ketogenic diet therapy reduced seizures in children with drug-resistant epilepsy, the randomized DIET trial showed. Median reduction in seizure burden was similar with the ketogenic...
In Epilepsy, Brain-Responsive Stimulation Passes Long-term Tests
Two new long-term studies, one an extension trial and the other an analysis of real-world experience, show that the RNS System direct brain responsive neurostimulator leads to reduction of seizure frequency in most epilepsy patients who had it implanted. Both studies...
FDA Approves New Indication for Drug Containing an Active Ingredient Derived from Cannabis to Treat Seizures in Rare Genetic Disease
SILVER SPRING, Md., July 31, 2020 /PRNewswire/ -- Today, the U.S. Food and Drug Administration approved Epidiolex (cannabidiol) [CBD] oral solution for the treatment of seizures associated with tuberous sclerosis complex (TSC) in patients one year of age and...
Poor Sleep Quality, Care Management Linked With Worsening of Seizure in Patients With Epilepsy
Amid the coronavirus disease 2019 (COVID-19) pandemic in Italy, a significant number of patients with epilepsy reported difficulties managing their condition, especially those who reported greater use of antiseizure medications (ASMs) forchronic therapy and poor sleep...
Looks like Epilepsy but Isn’t: Disease that is Deadly, Largely Undiagnosed and Untreated
One in four people who are tested for epilepsy do not have the disease but instead have a psychological condition called psychogenic non-epileptic seizures (PNES). Today (July 21, 6 am) in the prestigious journal, Neurology, Monash researchers describe the disease,...
Fenfluramine: New Drug Approved for Kids With Severe Epilepsy and Dravet Syndrome
What to know about fenfluramine. IN JUNE, THE U.S. FOOD and Drug Administration approved the medication fenfluramine for people with severe epilepsy and Dravet syndrome, or SCN1A-related seizure disorders, who are 2 years of age or older. Approval was based on the...
How to navigate epilepsy care
Despite the development of several new anti-seizure medications or anti-epileptic drugs over the past couple of decades, approximately 30 to 40% of epilepsy patients remain refractory—or resistant to medical treatment. In addition to the burden of having seizures,...
REM Sleep Duration Tied to Mid-Term Mortality Risk — Unclear if intervention would make a difference, however.
Less REM sleep was linked with greater mortality risk in middle-age and older adults. Every 5% reduction in REM sleep was tied to a 13% higher mortality rate in older men (age-adjusted HR 1.12; fully adjusted HR 1.13, 95% CI 1.08-1.19) over about 12 years, according...
New vitamin K-based drug shows promise against medication-resistant epilepsy
Researchers at the Medical University of South Carolina have formulated a vitamin K-based compound that, due to its unique structure and mechanism, eliminates medication-resistant epileptic seizures in mice tested to date. In the cover article of the June 11 issue of...
New Data Back Use of Medical Cannabis for Epilepsy, Pain, Anxiety
Two new studies offer positive news about medical cannabis, suggesting that marijuana products improve physical and cognitive symptoms, boost quality of life, and rarely produce signs of problematic use. In one study, patients with epilepsy who used medical cannabis...
GIRK channel activator can provide potential treatments for brain disorders
Potassium channels play an important role in controlling the electrical activity of neurons in the brain. We identified and characterized a new compound, called GiGA1, that selectively opens a subclass of potassium channels and can functionally suppress seizures in an...
Discovery of new step in how brain cells work could lead to new therapies for epilepsy
Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy. The study was led by researchers at FutureNeuro,...
Brain receptor pulls open electrical gate like a puppet master
For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain development and function, the receptor...
International study discovers three potential new targets for treating epilepsy
Dublin, 25 June 2020: A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be...
