Category: "SUDEP"

New treatment option available for Dravet syndrome

New treatment option available for Dravet syndrome

Global biopharma company UCB says the UK’s National Institute for Healthcare Excellence (NICE) has issued a positive Final Appraisal Determination (FAD) for its FINTEPLA (fenfluramine) oral solution. FINTEPLA is used for the treatment of seizures associated with Dravet syndrome as an add-on therapy to other anti-epileptic medicines for patients two years of age and older. […]

Annual reviews, ketogenic diet and urgent referral for breakthrough seizures among changes to epilepsy guidelines

Annual reviews, ketogenic diet and urgent referral for breakthrough seizures among changes to epilepsy guidelines

People with well controlled epilepsy may not be offered an annual review, according to the updated guidelines for epilepsy healthcare professionals from The National Institute for Health and Care Excellence (NICE). NICE now recommends that regular reviews (at least once a year) a should be offered to certain groups of people with epilepsy, according to […]

Mini biopsies point to source of lethal seizures in model mice

Mini biopsies point to source of lethal seizures in model mice

Impaired electrical signaling from a subtype of neuron may contribute to the deadly seizures associated with Dravet syndrome, according to a new study in mice. Dravet syndrome is a severe form of epilepsy typically caused by mutations in the SCN1A gene, which encodes a subunit of a sodium channel that neurons need to generate and propagate action potentials. About a quarter […]

Scientists expose lethal link between irregular heartbeats and epilepsy

Scientists expose lethal link between irregular heartbeats and epilepsy

A collaborative trial led by researchers at Monash University and Alfred Health, in collaboration with the Royal Melbourne Hospital has detected a high incidence of irregular heartbeats that can lead to cardiac arrest in people with chronic drug-resistant epilepsy, providing a new pathway for preventative treatment. The breakthrough finding suggests there is a link between […]

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