Category: "Genetic sequencing"

Taken during pregnancy, Topiramate, an antiepileptic drug, increases the risk of autism in children, warns the ANSM

Taken during pregnancy, Topiramate, an antiepileptic drug, increases the risk of autism in children, warns the ANSM

The risk of autistic disorders in children is increased more than two and a half times when Topiramate is consumed during pregnancy. This drug, used to treat epilepsy, also more than triples the risk of intellectual disability, a study has found. Topiramate, used to treat epilepsy or migraine, causes neurodevelopmental disorders in children exposed to […]

Focus On With Dr. Sadek: Genetics of Epilepsy part 1 & 2

Focus On With Dr. Sadek: Genetics of Epilepsy part 1 & 2

As science and medicine continue to advance, so does the knowledge for the role genetics may play in epilepsy. While many people with epilepsy often worry if they will pass their epilepsy to future generations, they should be reassured that this risk is typically quite low. Inherited vs. Mutations It is important to distinguish that […]

Potassium Channel Dysfunction in Genetic Epilepsy

Potassium Channel Dysfunction in Genetic Epilepsy

Northwestern Medicine scientists have discovered functional links between dozens of potassium channel gene variants and neonatal epilepsy, according to a study published in JCI Insight. The findings represent a significant advancement in the understanding of the gene KCNQ2, according to Alfred George, Jr., MD, chair and Alfred Newton Richards Professor of Pharmacology and lead author of the study. KCNQ2 was among the first genes […]

RESEARCHERS LOCATE 440 GENES THAT DEVELOP EACH BRAIN DIFFERENTLY

RESEARCHERS LOCATE 440 GENES THAT DEVELOP EACH BRAIN DIFFERENTLY

Large-scale MRI and genetic datasets are helping us understand the common variants of the genes that help build the human cerebral cortex To map regions of the brain to specific genes, researchers at the University of California – San Diego did genome-wide association studies (GWAS) of the regional cortical surface area and thickness of 39,898 adults and […]

Can You Inherit Epilepsy?

Can You Inherit Epilepsy?

Genetics of Epilepsy As science and medicine continue to advance, so does the knowledge for the role genetics may play in epilepsy. While many people with epilepsy often worry if they will pass their epilepsy to future generations, they should be reassured that this risk is typically quite low. Inherited vs. Mutations It is important […]

Genetic Tests Prompt Therapy Adjustments in Epilepsy

Genetic Tests Prompt Therapy Adjustments in Epilepsy

Physicians at a Boston hospital adjusted medical management for nearly three-quarters of patients with infantile- or childhood-onset epilepsy who were diagnosed with genetic epilepsy, researchers reported at the annual meeting of the American Epilepsy Society. The findings provide new insight into the usefulness of genetic tests in children with epilepsy of unknown cause. “Genetic testing is […]

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