We have been posting about using Zebrafish to model epilepsy treatment since 2013, and about the potential for treatments to be developed from these models. Fast forward to 2017, and we have a viable treatment in clinical trials! Via News Medical: New drug discovered in zebrafish model of pediatric epilepsy shows promising results in clinical […]
Researchers have published a paper which suggests the ancient Chinese remedy of magnolia bark could help treat drug-resistant epilepsy. Researchers have published a paper in the journal ACS Chemical Neuroscience that states they have found a potential new treatment for drug-resistant epilepsy by turning to the traditional Chinese medicine of Magnolia officinalis. Tests of 14 extracts from plants […]
Scientific study proves the relevance of glial cells for epileptic seizures and shows potential for new therapies The study investigated epileptic seizures in zebrafish – a widely used model organism for modelling human brain physiology. Zebrafish contains the same cell types that are present also in human brains. Two of these cell types are glia […]
With funding from NIH Phase II SBIR grant, Neuroene Therapeutics will take the next steps toward bringing their vitamin K analogues for drug-resistant epilepsy to clinical trial Neuroene Therapeutics, a start-up company founded by mitochondrial biologist Sherine S. L. Chan, Ph.D. and medicinal chemist C. James Chou, Ph.D. of the Medical University of South Carolina, […]
The Brienomyrus brachyistius, a fish commonly referred to as baby whales, uses electrical charges to communicate with and sense the world around them. Understanding how these African fish create electrical discharges could help researchers find new treatments for epilepsy. Photo Credit: Univ. of Michigan “Nerve impulses typically last one millisecond, but the baby whale and […]
New treatments for epilepsy are sorely needed because current medications don’t work for many people with the disease. To find new leads, researchers have now turned to the sea — a source of unique natural products that have been largely untapped for prospective drugs. The scientists report in the journal ACS Chemical Neuroscience that two […]
The U.S. Food and Drug Administration has granted Orphan Drug Designation to EPX-100 and EPX-200 for the treatment of patients with Dravet syndrome. Dravet Syndrome qualifies as a rare pediatric disease under Section 529 of Food, Drug, and Cosmetic Act. The rare, catastrophic, lifelong form of epilepsy begins in the first year of life with […]
Piper Wood had her first seizure in a setting meant for sunscreen, snorkels, shovels, and pails. The island was remote – that was the point of this family vacation. Six months old and turning blue, Piper finally calmed down and drew breath again after the island’s well-trained doctor brought her hour-long seizure to a halt […]
A single gene that coordinates a network of about 400 genes involved in epilepsy could be a target for new treatments, according to research. Epilepsy is a common and serious disease that affects around 50 million people worldwide. The mortality rate among people with epilepsy is two to three times higher than the general population. […]
Febrile seizures are among the most dreaded complications of infectious diseases in small children. An international research team composed of experts from the Universities of Tübingen, Leuven and Luxembourg has now made a breakthrough by demonstrating the existence of a previously unknown cause for this most frequent form of epileptic attacks in small children. As […]
