Welcome to EpilepsyU.com a social network dedicated to the epilepsy community

Side Effects of Medication

Epilepsy drug (Gabapentin/Neuronton) linked to opioid misuse

A recent study conducted by Duquesne University professor John Tomko has linked high dosages of the epilepsy drug Gabapentin to opioid abuse. Based on the findings of the study, Tomko recommends prescribing and distributing Gabapentin with more scrutiny and oversight. Gabapentin, brand name Neurontin, has been formally approved by the Food and Drug Administration (FDA) to treat symptoms of epilepsy, such as seizures and post herpetic neuralgia, a type of pain caused by shingles. According to Tomko, however, Gabapentin has been used off-label (i.e., not approved by the FDA) to treat other ailments such as back pain, anxiety, bipolar disorder, migraines and more. Tomko’s study found that subjects in UPMC Mercy’s Behavioral Health units were twice as likely to test positive for illicit drug a...

AVOIDING SIDE EFFECTS: Trial Administers Epilepsy Drugs Directly to the Brain

WORLD-first trial will deliver medication directly into the brain of epilepsy patients to sidestep the ­devastating side-effects of tablets. The pioneering treatment aims to be a game-changer for neurological conditions more widely by getting a drug directly where it is needed. The St Vincent’s Hospital team has implanted a pump in their first ­patient. The pump sends anti-epileptic medication from the stomach, through a tiny tube, into a cavity in the brain where it can diffuse into the areas causing the “electrical storm”. READ FULL STORY: http://www.heraldsun.com.au/news/victoria/melbourne-epilepsy-trial-delivers-medication-directly-into-brain-to-sidestep-side-effects/news-story/13612af0fd456d18583b60cd16d3102e

Anti-epilepsy drugs can cause inflammations

Physicians at the Ruhr-Universität Bochum (RUB) have been investigating if established anti-epilepsy drugs have anti-inflammatory or pro-inflammatory properties – an effect for which these pharmaceutical agents are not usually tested. One of the substances tested caused stronger inflammations, while another one inhibited them. As inflammatory reactions in the brain may be the underlying cause for epileptic disorders, it is vital to take the trigger for the disorder under consideration when selecting drugs for treatment, as the researchers concluded. They published their report in the journal Epilepsia. Glial cells play a crucial role in the nervous system Hannes Dambach from the Department for Neuroanatomy and Molecular Brain Research, together with a team of colleagues, studied how anti-e...

CONSUMER AFFAIRS: Patients Report Issues with New Version of Topamax

Topiramate is a drug, also marketed under the brand name Topamax, that is used to treat certain types of seizures in people who have epilepsy. Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome, a disorder that causes seizures and developmental problems. It can also be used to prevent migraine headaches. It’s in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain and is a widely and successfully used drug. The drug is now generic and is produced by different pharmaceutical companies. Carol, of Lafayette, La., reports taking 100 mg twice daily for sciatic nerve pain. “I was getting Topiramate by Teva Pharmaceuticals and I was having very little discomfort once I went from once...