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ketogenic diet

Ketogenic diet may help treat epilepsy by altering the gut microbiota

The ketogenic diet is known to successfully treat epilepsy for many people. In a recent study, researchers determine how the ketogenic diet alters the gut microbiota and if this mediates the anti-seizure effects. The ketogenic diet is a low-carbohydrate, high-fat diet that puts the body into a metabolic state called ketosis. During ketosis, the body is starved of carbohydrates and is forced to generate ketone bodies from the breakdown of fat for energy. The ketogenic diet is popular for weight loss, and although the diet’s benefits in healthy people are controversial, the ketogenic diet has long been used to successfully treat epilepsy. However, it is unknown how adopting the ketogenic diet actually affects brain activity to prevent seizures. The gut microbiota is involved in metabolic and...

Is there a link between diabetes and the keto diet?

Is Keto diet: Scientists find link to diabetes risk It you have your child on, or you are doing, the Ketogenic Diet and not being monitored by a medical professional beware. “By finding a link to a condition that raises the risk of type 2 diabetes, new research questions the health benefits of ketogenic diets. Is there a link between diabetes and the keto diet?

A dietitian on what you need to know about the keto diet – Another Fad?

A diet developed in the 1920s to treat children with epilepsy is suddenly all the rage. The ketogenic diet, or “keto diet”, has reportedly been endorsed by celebrities and even athletes are giving it a go. The keto diet is one of a series of fashionable low carb diets that include the Atkins diet, the South Beach diet and the Zone diet. There are hundreds of people selling ketogenic diet plans online and on social media, with big promises of the results to be expected.

Gut bacteria play key role in anti-seizure effects of ketogenic diet

UCLA scientists have identified specific gut bacteria that play an essential role in the anti-seizure effects of the high-fat, low-carbohydrate ketogenic diet. The study, published today in the journal Cell, is the first to establish a causal link between seizure susceptibility and the gut microbiota—the 100 trillion or so bacteria and other microbes that reside in the human body’s intestines.

Diet May Help Fight Epilepsy When Meds Fail

For children with epilepsy who don’t find relief from their seizures with medication, a tightly controlled nutrition plan might help, a pair of new studies suggests.   Called the ketogenic diet, the therapy provides a carefully balanced high-fat, low-carbohydrate diet that causes the body to burn fat instead of carbohydrates for fuel. This changes the way brain cells use energy and helps to reduce seizures, according to the researchers.

What are ketogenic diets? Can they treat epilepsy and brain cancer?

Ketogenic diets are back in the news with claims they are a “cure-all”. Research shows that in epilepsy not controlled by current treatment, around 50% of children and adults following ketogenic diets have a reduction in seizures. For brain cancer, most research has been in animals. A number of human trials are underway testing safety, tolerance, interactions with other treatments, side-effects and the impact on cancer progression, quality of life and survival. So what are ketones? Although the main source of energy for the body is usually carbohydrate, which gets converted to blood glucose during digestion and metabolism, the body can also burn fat for energy. Ketone bodies, or ketones for short, are molecules produced by the liver when fat is metabolised. Ketones are used as ...

Research examines ketone esters to combat hyperbaric oxygen toxicity in Navy divers

For the first time, ketone esters-oral supplements useful in epilepsy treatment-are being studied to fight seizures caused by hyperbaric oxygen toxicity, a life-threatening byproduct of breathing too much oxygen that impacts deep-water divers. The Office of Naval Research (ONR) is sponsoring this research. “This work represents a renaissance in how therapies are repurposed for other applications,” said Dr. William D’Angelo, a program manager in ONR’s Undersea Medicine Program. “Traditionally, certain therapies were only used to treat specific conditions. There’s now a movement to explore how drugs and other therapies already approved by the Food and Drug Administration for one type of treatment could treat more than one ailment.”

BREAKTHROUGH: Amino Acid Appears to Block Seizures in Mice

Finding may pave way for much-needed treatments for people with epilepsy Finding suggests novel mechanism for treating epilepsy An amino acid whose role in the body has been all but a mystery appears to act as a potent seizure inhibitor in mice, according to a study by researchers at Johns Hopkins. In a series of experiments, the amino acid D-leucine, found in many foods and certain bacteria, interrupted prolonged seizures, a serious condition known as status epilepticus, and it did so just as effectively as the epilepsy drug diazepam — the choice of treatment for patients in the throes of convulsions — but without any of the drug’s sedative side effects. Results of the federally funded research, reported online June 4 in the journalNeurobiology of Disease, also suggest that D-leucine work...

Ketogenic Diet and Enzyme Inhibitors Treat Drug-Resistant Epilepsy

SOURCE – One percent of the world’s population suffer from epilepsy, and a third of sufferers cannot be treated with antiepileptic drugs (AEDs). Diet control has been used to treat patients suffering from drug-resistant epilepsy since the 1920s, but how metabolic processes affect epilepsy has not been fully understood. Now researchers at Okayama University and Kawasaki Medical School have identified the metabolic pathways altered by diet treatments, the enzymes that can control them and potential metabolic drugs that may be effective for treating types of epilepsy that are resistant to other drugs.

10 Year Study Shows Effectiveness of Ketogenic Diet

A new Australian study has offered the latest evidence of the long-term benefits that ketogenic diets can provide to patients with epilepsy. Led by the University of Wollongong, the research project aimed to evaluate efficacy, tolerability and compliance rates associated with three different types of ketogenic diets – the classical ketogenic diet, a medium-chain triglyceride (MCT) regime and the modified Atkins diet – over a ten-year period. High-fat, adequate-protein and low-carbohydrate diets of this kind have been shown to be an effective means of providing improved seizure control among people with difficult-to-control forms of epilepsy. However, there is also evidence that this type of diet can sometimes increase the risk of nephrolithiasis – the process that leads to the formation of...

Ketogenic Diet May Help Adults With Refractory Epilepsy

A ketogenic diet could help control refractory epilepsy in adults, according to research published online Oct. 29 in Neurology. THURSDAY, Oct. 30, 2014 (HealthDay News) — A ketogenic diet could help control refractory epilepsy in adults, according to research published online Oct. 29 inNeurology.

THE KETOGENIC DIET FOR ADULTS

Previously, the Ketogenic Diet has been primarily administered to children with epilepsy. Some of the reasons it has not been a staple for adult treatment is that there are some cardiovascular risks and children are able to recover from the treatment at a faster rate. Adults also have longer-term eating habits in place, which can be hard habits to change. An adult caretaker usually makes sure a child is adhering to the diet, doing all of the planning, purchasing, preparing and serving for the child.  An adult will have to take this diet seriously on their own and use their own self-control to adhere to the diet strictly. Furthermore, since several forms of pediatric epilepsy can be so severe and so drug-resistant, previous research has focused on pediatric treatment. There has not been muc...