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Chuck Carmen wrote a new post, Low-dose fish oil regimen reduces epileptic seizures by 33.6%!, on the site EpilepsyU 1 day, 18 hours ago
A new study completed by UCLA reports that fish oil could help patients who struggle with epileptic seizures. A randomized controlled study reported that low doses of omega-3 fatty acids decrease the frequency of seizures. (1)
Participants of the study took three fish oil capsules per day at 1080 mg each dose. Participants found a significant reduction in the incident of seizures. Previous studies using high doses of omega-3 fatty acids found no significant reduction in seizures. Sometimes less really is more! The new results surprised researchers. They found that omega-3 fatty acids show the ability to cross into the central nervous system and block calcium and sodium channels within nerve cells. This prevents the repetitive firing of cells that cause seizures. (1)
Christopher DeGiorgio, professor of neurology at UCLA, reported that patients with epilepsy have a higher risk of sudden death from heart disease and fish oil may reduce this risk and protect against heart disease. Omega-3 fatty acids have the ability to cross through the bloodstream into heart cells and stabilize the heart rhythm, protect against heart attacks and myocardial infarction. (1)
“The American Heart Association has issued a guideline indicating that around 1080 mg of omega-3 fatty acids per day, equivalent to 3 fish oil capsules, is effective in reducing the risk of cardiovascular disease, and fish oil is commonly administered to patients who have prior myocardial infarctions, irregular heartbeats, and very high triglyceride levels,” DeGiorgio said. “So I thought that since 1000 mg of omega-3 fatty acids is effective for heart disease, we should evaluate it and a higher dose to see which, if any, was effective for epilepsy seizure.” (1)
Low-dose fish oil decreased seizures by 33.6%, while two patients report being seizure free!
The study involved 24 participants diagnosed with epilepsy who received no benefits from traditional treatment. Each participant received three 10-week treatments that were spaced 6 weeks apart. (2,3)
Patients taking the low-dose fish oil saw a 33.6% decrease in seizures, compared to the placebo group. Two patients on the low dose fish oil reported being completely seizure-free during the 10-week treatment sessions. The high dose fish oil produced no significant findings. Those taking the low dose fish oil also noticed a small drop in blood pressure, whereas the participants who consumed high doses of fish oil noticed a small increase in blood pressure. (1)
“We don’t completely understand why low dose works and higher doses do not, but there is evidence from animal studies that high doses are counterproductive. The response to fish oil at low dose for both seizures and depression has substantial implications for use, given the common propensity for individuals to self-dose with a ‘…a little helps, a lot should help much more’ thought process,” DeGiorgio said. (1)
Source: Raw Food World
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A new study that researched the correlation between pediatric vaccinations and seizures found that if seizures were triggered by vaccines, the majority were found to have an underlying cause, predisposing them to developing seizures/epilepsy.
1. The majority of children (65%) diagnosed with new-onset epilepsy related to the administration of vaccinations were found to have an underlying genetic or structural neurological disorder which predisposed them to developing epilepsy.
2. The etiologies for underlying epilepsy disorders unmasked by vaccination included: chromosomal deletions, neuronal migration disorders, Dravet Syndrome (severe myoclonic epilepsy of infancy), and familial febrile and infantile epilepsy disorders.
OBJECTIVES: This study was an assessment of the incidence, course, and etiology of epilepsy with vaccination-related seizure onset in a population-based cohort of children.
METHODS: The medical data of 990 children with seizures after vaccination in the first 2 years of life, reported to the National Institute for Public Health and Environment in the Netherlands in 1997 through 2006, were reviewed. Follow-up data were obtained of children who were subsequently diagnosed with epilepsy and had had seizure onset within 24 hours after administration of an inactivated vaccine or 5 to 12 days after a live attenuated vaccine.
RESULTS: Follow-up was available for 23 of 26 children (median age: 10.6 years) with epilepsy onset after vaccination. Twelve children developed epileptic encephalopathy, 8 had benign epilepsy, and 3 had encephalopathy before seizure onset. Underlying causes were identified in 15 children (65%) and included SCN1A–related Dravet syndrome (formerly severe myoclonic epilepsy of infancy) or genetic epilepsy with febrile seizures plus syndrome (n = 8 and n= 1, respectively), a protocadherin 19 mutation, a 1qter microdeletion, neuronal migration disorders (n = 2), and other monogenic familial epilepsy (n= 2).
CONCLUSIONS: Our results suggest that in most cases, genetic or structural defects are the underlying cause of epilepsy with onset after vaccination, including both cases with preexistent encephalopathy or benign epilepsy with good outcome. These results have significant added value in counseling of parents of children with vaccination-related first seizures, and they might help to support public faith in vaccination programs.