Category: "Research"

Genetic study of epilepsy points to potential new therapies

Genetic study of epilepsy points to potential new therapies

The largest study of its kind, led by international researchers including scientists at RCSI (Royal College of Surgeons in Ireland), has discovered 11 new genes associated with epilepsy.   The research is published in today’s issue of Nature Communications. It greatly advances knowledge of the underlying biological causes of epilepsy and may inform the development of […]

Scientists solve century-old neuroscience mystery—answers may lead to epilepsy treatment

Scientists solve century-old neuroscience mystery—answers may lead to epilepsy treatment

Scientists at the Virginia Tech Carilion Research Institute have solved a 125-year-old mystery of the brain, and, in the process, uncovered a potential treatment for acquired epilepsy. Since 1893, scientists have known about enigmatic structures called perineuronal nets wrapped around neurons, but the function of the nets remained elusive. Now, a research team led by […]

The Role Of Autoantibodies In Epilepsy

The Role Of Autoantibodies In Epilepsy

The immune system normally protects a person from infections by making specialised agents called antibodies which normally recognise “foreign targets” and destroy them. Doctors utilise this function through vaccinations, which are used for immunization. Sometimes, the immune system can become “over-excited” and instead of attacking foreign bodies it attacks its own tissues, causing a disease, […]

Neuroene Therapeutics awarded $1.5 million to develop anti-seizure compound for epilepsy

Neuroene Therapeutics awarded $1.5 million to develop anti-seizure compound for epilepsy

With funding from NIH Phase II SBIR grant, Neuroene Therapeutics will take the next steps toward bringing their vitamin K analogues for drug-resistant epilepsy to clinical trial Neuroene Therapeutics, a start-up company founded by mitochondrial biologist Sherine S. L. Chan, Ph.D. and medicinal chemist C. James Chou, Ph.D. of the Medical University of South Carolina, […]

New causative gene found in severe childhood epilepsy

New causative gene found in severe childhood epilepsy

A large international research team has discovered a new genetic cause for a severe, difficult-to-treat childhood epilepsy syndrome. Spontaneous mutations in one gene disrupt the flow of calcium in brain cells, resulting in epileptic overactivity. The team’s research in patients also found clues to potential medical treatments for the rare condition. “Even though variants in […]

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