Category: "Pregnancy"

Exposure to Valproate Risk for Attention-Deficit/Hyperactivity Disorder

Exposure to Valproate Risk for Attention-Deficit/Hyperactivity Disorder

What is the risk of attention-deficit/hyperactivity disorder in children prenatally exposed to valproate (Depakote) and other antiepileptic drugs? In a population-based study of 913,302 children in Denmark, prenatal exposure to valproate was significantly associated with a 48% increased risk of attention-deficit/hyperactivity disorder compared with children with no valproate exposure. No association was identified for other […]

Vast Majority of Women With Epilepsy Able to Get Pregnant

Vast Majority of Women With Epilepsy Able to Get Pregnant

The vast majority of women with epilepsy are able to get pregnant, with relatively few issues, new research shows. “There has been the notion and some evidence in the past that fertility is reduced in women with epilepsy compared with the general population, but what these findings suggest is that 90% of women with epilepsy can get […]

Some Types of Epilepsy Pose More Risks During Pregnancy

Some Types of Epilepsy Pose More Risks During Pregnancy

Women with frontal lobe epilepsy are much more likely to have an increase in seizures during pregnancy than those with focal epilepsy or generalized epilepsy, researchers report. “Physicians need to monitor women with focal epilepsy — especially frontal lobe epilepsy — more closely during pregnancy because maintaining seizure control is particularly challenging for them,” said […]

Spontaneous Fetal Loss Risk Doubled for Women with Epilepsy

Spontaneous Fetal Loss Risk Doubled for Women with Epilepsy

Unplanned pregnancy in women who have epilepsy may double the risk for spontaneous fetal loss, according to a new study. Investigators from the Harvard Neuroendocrine Unit at Massachusetts General Hospital in Boston, Massachusetts, examined the Epilepsy Birth Control Registry (EBCR) in order to determine whether a planned pregnancy is a determinant for spontaneous fetal loss […]

Childhood Seizures After Phototherapy

Childhood Seizures After Phototherapy

A follow-up study of Danish babies with neonatal hyperbilirubinaemia* who had been treated with phototherapy discovered a modest increase in the risk of childhood epilepsy. The finding has now been replicated in a large database analysis from the United States. Phototherapy is associated with an increase in the likelihood of epilepsy by 30% to 40% […]

Just the right dose: antiepileptic drug clearance changes during pregnancy

Just the right dose: antiepileptic drug clearance changes during pregnancy

Study finds significant changes in how seizure medications are metabolized during the different trimesters of pregnancy BRIGHAM AND WOMEN’S HOSPITAL During pregnancy, the numerous physiological changes a woman’s body undergoes can alter the way medications are metabolized, the rate at which they are cleared, and their overall effectiveness. Many women continue taking antiepileptic drugs (AEDs) […]

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