Category: "Neurology"

FDA Update: Anti-epileptic drug efficacy in adults can be extrapolated to pediatric patients

FDA Update: Anti-epileptic drug efficacy in adults can be extrapolated to pediatric patients

From the Food and Drug Administration Office of Pediatric Therapeutics, Division of Pediatric and Maternal Health, Division Neurology Products and Office of Clinical Pharmacology Expansion of the indication for anti-epileptic drugs to pediatric patients with partial onset seizure (POS) frequently follows adult approval and typically is supported by at least one adequate and well-controlled clinical […]

Invading the brain to understand and repair cognition

Invading the brain to understand and repair cognition

April 5, 2016, New York – People are using brain-machine interfaces to restore motor function in ways never before possible – through limb prosthetics and exoskletons. But technologies to repair and improve cognition have been more elusive. That is rapidly changing with new tools – from fully implantable brain devices to neuron-eavesdropping grids atop the […]

Neuron type-specific gene loss linked to Angelman syndrome seizures

Neuron type-specific gene loss linked to Angelman syndrome seizures

The gene UBE3A plays a critical role in early neurological development. If UBE3A is overexpressed – or if the enzymatic function of UBE3A protein is hyperactive – autism ensues. A lack of functional UBE3A causes Angelman syndrome (AS), a neurodevelopmental disorder characterized by severe developmental delay, motor deficits, absence of speech, and, in most cases, […]

Aging brings another fear – epilepsy

Aging brings another fear – epilepsy

Disease can be harder to diagnose and treat because it can be masked by other health issues common in older patients: Rapidly approaching their senior years, baby boomers are entering a new stage of life and facing a host of new health risks. The implications of having a large population of senior adults include the […]

Neuron type-specific gene loss linked to Angelman syndrome seizures

Neuron type-specific gene loss linked to Angelman syndrome seizures

The gene UBE3A plays a critical role in early neurological development. If UBE3A is overexpressed – or if the enzymatic function of UBE3A protein is hyperactive – autism ensues. A lack of functional UBE3A causes Angelman syndrome (AS), a neurodevelopmental disorder characterized by severe developmental delay, motor deficits, absence of speech, and, in most cases, […]

New cytoplasmic role for proteins linked to neurological diseases, cancers

New cytoplasmic role for proteins linked to neurological diseases, cancers

Researchers at UT Southwestern Medical Center have identified a second role for a class of RNA-binding proteins, revealing new insights about neurological diseases and conditions associated with this protein such as autism, epilepsy, and certain types of cancer. “These data should promote a re-evaluation of those diseases to see if this new function that we’ve […]

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