Category: "Medicine"

FDA Approves Stiripentol for Dravet Syndrome Seizures

FDA Approves Stiripentol for Dravet Syndrome Seizures

The US Food and Drug Administration today approved stiripentol (Diacomit) for the treatment of seizures associated with Dravet syndrome epilepsy. This is just the second approved form of treatment specifically for patients with Dravet syndrome. The drug is approved for use in patients 2 years of age and older who are taking clobazam. Stiripentol is […]

Early Treatment Failure More Likely With Carbamazepine vs Lamotrigine in Epilepsy

In patients with epilepsy, moderate-quality evidence indicates that treatment failure for any reason related to therapy or adverse events (AEs) occurs significantly earlier with carbamazepine than with lamotrigine, although the results for time to first seizure imply that carbamazepine may be superior to lamotrigine for seizure control. Results of the review were published in the Cochrane Database of Systematic […]

FDA To Consider Midazolam Nasal Spray for Acute Cluster Seizure Treatment

FDA To Consider Midazolam Nasal Spray for Acute Cluster Seizure Treatment

The US Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) for an investigational nasal spray therapy intended for the acute treatment of seizure clusters. Midazolam Nasal Spray—from global biopharmaceutical company UCB, Brussels, Belgium (UCB)—has been previously granted Orphan Drug and Fast Track designations by the FDA. It’s now set for a […]

UCB Announces BRIVIACT® (Brivaracetam) now Approved by FDA to Treat Partial-onset (Focal) Seizures in Pediatric Epilepsy Patients

UCB Announces BRIVIACT® (Brivaracetam) now Approved by FDA to Treat Partial-onset (Focal) Seizures in Pediatric Epilepsy Patients

BRIVIACT® (brivaracetam) CV oral formulations are approved as a monotherapy or adjunctive therapy in patients four years of age and older with partial-onset seizures   – Approval provides pediatric epilepsy patients a treatment option which can be initiated at a therapeutic dose from day one   – Pediatric epilepsy is the most common, serious neurological […]

Antiepileptic drugs linked with an increased risk of Alzheimer’s and dementia, says research

Antiepileptic drugs linked with an increased risk of Alzheimer’s and dementia, says research

According to a new study from the University of Eastern Finland and the German Center for Neurodegenerative Diseases, DZNE, antiepileptic drugs are associated with an increased risk of Alzheimer’s disease and dementia.   The clinical investigation, led by Heidi Taipale from the University of Eastern Finland, evaluated the data of nearly 100,000 individuals with dementia […]

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