Women with frontal lobe epilepsy are much more likely to have an increase in seizures during pregnancy than those with focal epilepsy or generalized epilepsy, researchers report. “Physicians need to monitor women with focal epilepsy — especially frontal lobe epilepsy — more closely during pregnancy because maintaining seizure control is particularly challenging for them,” said […]
The rate of miscarriage was doubled in women with epilepsy whose pregnancies were unplanned, a survey of Epilepsy Birth Control Registry participants found. Among women with epilepsy, spontaneous fetal loss occurred in 35% of unplanned versus 16% of planned pregnancies, reported Andrew Herzog, MD, MSc, of Beth Israel Medical Center in Boston, and colleagues in JAMA Neurology. “This […]
Not using folic acid before and during pregnancy increased risks substantially. Supplemental folic acid before pregnancy and during the first trimester may limit language development problems in children exposed to anti-epileptic drugs in utero. Note that the study suggests that beginning supplemental folic acid prior to pregnancy and continuing it through at least the first […]
Catamenial epilepsy is a form of seizure disorder which is related to the hormonal changes during menstrual cycling in normal women. It has been found to account for about a third of women with epilepsy.
Exposure to sodium valproate or a combination of antiepileptic drugs (AEDs) in utero is associated with worse attainment on national educational tests for 7-year-olds, according to a study published online March 26 in the Journal of Neurology, Neurosurgery & Psychiatry. Arron S. Lacey, from Swansea University Medical School in the United Kingdom, and colleagues identified […]
Prenatal Folic Acid Supplementation Found to Reduce Risk of Autistic Traits in Children of Women Taking AEDs
Prenatal folic acid supplements were found to reduce the risk of autistic traits in children born to women who were taking antiepileptic drugs while pregnant, according to a study published online on December 26 in JAMA Neurology. The risk was less for these women compared with those who did not take folic acid supplements.