What is the risk of attention-deficit/hyperactivity disorder in children prenatally exposed to valproate (Depakote) and other antiepileptic drugs? In a population-based study of 913,302 children in Denmark, prenatal exposure to valproate was significantly associated with a 48% increased risk of attention-deficit/hyperactivity disorder compared with children with no valproate exposure. No association was identified for other […]
The vast majority of women with epilepsy are able to get pregnant, with relatively few issues, new research shows. “There has been the notion and some evidence in the past that fertility is reduced in women with epilepsy compared with the general population, but what these findings suggest is that 90% of women with epilepsy can get […]
Women with frontal lobe epilepsy are much more likely to have an increase in seizures during pregnancy than those with focal epilepsy or generalized epilepsy, researchers report. “Physicians need to monitor women with focal epilepsy — especially frontal lobe epilepsy — more closely during pregnancy because maintaining seizure control is particularly challenging for them,” said […]
The rate of miscarriage was doubled in women with epilepsy whose pregnancies were unplanned, a survey of Epilepsy Birth Control Registry participants found. Among women with epilepsy, spontaneous fetal loss occurred in 35% of unplanned versus 16% of planned pregnancies, reported Andrew Herzog, MD, MSc, of Beth Israel Medical Center in Boston, and colleagues in JAMA Neurology. “This […]
Not using folic acid before and during pregnancy increased risks substantially. Supplemental folic acid before pregnancy and during the first trimester may limit language development problems in children exposed to anti-epileptic drugs in utero. Note that the study suggests that beginning supplemental folic acid prior to pregnancy and continuing it through at least the first […]
Catamenial epilepsy is a form of seizure disorder which is related to the hormonal changes during menstrual cycling in normal women. It has been found to account for about a third of women with epilepsy.