Category: "Childhood Epilepsy"

FDA To Consider Midazolam Nasal Spray for Acute Cluster Seizure Treatment

FDA To Consider Midazolam Nasal Spray for Acute Cluster Seizure Treatment

The US Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) for an investigational nasal spray therapy intended for the acute treatment of seizure clusters. Midazolam Nasal Spray—from global biopharmaceutical company UCB, Brussels, Belgium (UCB)—has been previously granted Orphan Drug and Fast Track designations by the FDA. It’s now set for a […]

Spider venom strikes a blow against childhood epilepsy

Spider venom strikes a blow against childhood epilepsy

A devastating form of childhood epilepsy that is resistant to traditional drugs may have met its match in spider venom. Researchers from The University of Queensland and the Florey Institute of Neuroscience and Mental Health discovered that a peptide in spider venom can restore the neural deficiencies that trigger seizures associated with Dravet syndrome. UQ […]

Early-Life Seizures Prematurely Wake Up Brain Networks Tied to Autism

Early-Life Seizures Prematurely Wake Up Brain Networks Tied to Autism

Antiepileptic Drug May Keep Synapses ‘Silent’ Longer So Brain Can Develop Normally, Penn Study Suggests   Early-life seizures prematurely switch on key synapses in the brain that may contribute to further neurodevelopmental delay in children with autism and other intellectual disabilities, suggests a new study from researchers at Penn Medicine published online in Cell Reports. […]

Immune Response May Contribute to Pediatric Epilepsy

Immune Response May Contribute to Pediatric Epilepsy

Irregular concentrations of T-cells in the brain contribute to the development of seizures in pediatric epilepsy, according to a Northwestern Medicine study published in the Journal of Experimental Medicine.   The experiments suggest anti-inflammatory drugs should be considered for therapy, in addition to the anti-seizure drugs that are typically prescribed, according to Stephen D. Miller, […]

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