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seizures

Local epileptic seizure shows long distance interaction

An epileptic seizure may be highly local, but it also influences brain activity at a distance of over ten centimeters from the core. This, in turn, affects the active area, scientists of the University of Twente and the University of Chicago show in the Proceedings of the National Academy of Sciences (PNAS). The area in which an epileptic seizure starts in the brain, may be small but it reaches other parts of the brain at distances of over 10 centimeters. That distant activity, in turn, influences the epileptic core, according to mathematicians and neurologists of the University of Twente and the University of Chicago.

Epilepsy Treatment Often Delayed in Older Adults

A new study published in Epilepsia found that although most newly diagnosed cases of epilepsy in older adults are treated appropriately with monotherapy, only half of those patients receive treatment within the recommended time frame, and a substantial portion were prescribed older antiepileptic drugs (AEDs) despite recommendations to use newer AEDs in this population.

Psychiatric Manifestations of Frontal Lobe Epilepsy

BETHESDA, Md., Jan. 12, 2017 /PRNewswire-iReach/ — Frontal lobe epilepsy (FLE) comprises 30% of all partial epilepsies; it can masquerade as a primary psychiatric condition or be co-morbid with a psychiatric illness.

Specific Brain Lesion Linked to Post-Stroke Epilepsy

HOUSTON — Researchers may have identified a common pathologic lesion in many patients with post-stroke epilepsy (PSE).

Puzzle of Impaired Consciousness in Absence Epilepsy Solved?

Intense abnormal activity in well-known brain networks that occurs early in a seizure may be the key to impaired consciousness in children with absence epilepsy, new research suggests.

Neuroscientists uncover how the brain retunes to pull meaning out of noisy environment

When you’re suddenly able to understand someone despite their thick accent, or finally make out the lyrics of a song, your brain appears to be re-tuning to recognize speech that was previously incomprehensible.

Seizure Triggers: Research Sheds Lights on How Certain Stimuli Cause Seizures

Why does exposure to rhythmic stimulation at certain frequencies facilitate the occurrence of epileptic seizures?

First-Line Treatment With Carbamazepine in Neonatal Epilepsy

Low-dose carbamazepine (CBZ) should be considered as first-line treatment for benign familial neonatal epilepsy (BNFE), even in cases of status epilepticus, according to data reported recently in Epilepsia. The majority of neonates given CBZ 10 mg/d as needed responded within hours of administration and remained seizure free with continued treatment for up to 16 years.

Study improves molecular understanding of the brain in people with epilepsy

Neural stem cells have been found in epileptic brain tissue—outside the regions of the brain where they normally reside. In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from Sahlgrenska Academy.

Research at Stanford locates absence epilepsy seizure ‘choke point’ in brain

A particular structure in the brain is a “choke point” for a type of epileptic seizure that affects mostly children, Stanford University School of Medicine investigators have found. The researchers used an advanced technology called optogenetics to show, in rodent models of one of the most common forms of childhood epilepsy, that inducing synchronized, rhythmic activity in a specific nerve tract within this structure is sufficient to cause seizures, while disrupting that activity is sufficient to terminate them.

AVOIDING SIDE EFFECTS: Trial Administers Epilepsy Drugs Directly to the Brain

WORLD-first trial will deliver medication directly into the brain of epilepsy patients to sidestep the ­devastating side-effects of tablets. The pioneering treatment aims to be a game-changer for neurological conditions more widely by getting a drug directly where it is needed. The St Vincent’s Hospital team has implanted a pump in their first ­patient. The pump sends anti-epileptic medication from the stomach, through a tiny tube, into a cavity in the brain where it can diffuse into the areas causing the “electrical storm”. READ FULL STORY: http://www.heraldsun.com.au/news/victoria/melbourne-epilepsy-trial-delivers-medication-directly-into-brain-to-sidestep-side-effects/news-story/13612af0fd456d18583b60cd16d3102e

Seizures Vs. Epilepsy: Risks, Differences, And Treatments

Seizures and epilepsy often overlap, so it’s easy to mistake one for the other. However, there are key differences between these medical terms, and understanding them could mean the difference between life and death for those who are affected. Here is a brief overview of seizures and epilepsy to help you better understand the conditions. HOW DO THEY DIFFER The main difference between a seizure and epilepsy is that seizures are a single occurrence while epilepsy is a medical condition. Though seizures are one of the most characteristic symptoms of epilepsy, not everyone who has seizures suffers from epilepsy. In the case of a seizure, small disruptions in neuron interactions can cause twitches or spasms. The sudden electrical discharges in the brain can cause changes in behavior and conscio...

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