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Stereo EEG provides a deep, detailed map of the brain as physicians evaluate patients for the surgical treatment of epilepsy.

For patients that find their seizures difficult to manage on medications, other treatment options such as diet, devices or surgery may be beneficial. Dr. Amy Crepeau, neurologist at Mayo Clinic in Arizona, discusses the evaluation of patients with epilepsy using brain mapping technology.

Puzzle of Impaired Consciousness in Absence Epilepsy Solved?

Intense abnormal activity in well-known brain networks that occurs early in a seizure may be the key to impaired consciousness in children with absence epilepsy, new research suggests.

UAB researchers launch first drug study to prevent onset of epilepsy in children with TSC

Researchers at the University of Alabama at Birmingham have launched the first drug study aimed at preventing or delaying the onset of epilepsy in children with a genetic condition known as tuberous sclerosis complex. UAB is the lead institution and data center for the PREVeNT study, a national, multisite study funded by a $7 million grant from the National Institutes of Health. Tuberous sclerosis complex is a genetic disorder that causes tumors to form in many different organs. TSC particularly affects neurologic functions, often leading to seizures, developmental delay, intellectual disability and autism. About 80 percent of children with TSC develop epilepsy within the first three years of life.

INTERVIEW: Distinguishing Epilepsy From its Imitators with EEG

In this interview, Dr. Andrew N. Wilner, MD, interviews Dr. Joseph F. Drazkowski, MD who is involved with the American Academy of Neurology developing courses for neurologists, for increasing proficiency in EEG and EEG video. Excerpt from Medscape:

Texting Can Change Brain Waves

Textual communication using smartphones can change rhythm of brain waves Sending text messages on a smartphone can change the rhythm of brain waves, according to a new study published in Epilepsy & Behavior. People communicate increasingly via text messaging, though little is known on the neurological effects of smartphone use. To find out more about how our brains work during textual communication using smartphones, a team led by Mayo Clinic researcher William Tatum analyzed data from 129 patients. Their brain waves were monitored over a period of 16 months through electroencephalograms (EEGs) combined with video footage. Dr. Tatum, professor of neurology and director of the epilepsy monitoring unit and epilepsy center at Mayo Clinic in Jacksonville, Florida found a unique ‘text...

BRAIN TECH: Carbon Electrodes Proven to Be Safe Brain Implants

Researchers have successfully demonstrated how it is possible to interface graphene – a two-dimensional form of carbon – with neurons, or nerve cells, while maintaining the integrity of these vital cells. The work may be used to build graphene-based electrodes that can safely be implanted in the brain, offering promise for the restoration of sensory functions for amputee or paralysed patients, or for individuals with motor disorders such as epilepsy or Parkinson’s disease. The research, published in the journal ACS Nano, was an interdisciplinary collaboration coordinated by the University of Trieste in Italy and the Cambridge Graphene Centre. Previously, other groups had shown that it is possible to use treated graphene to interact with neurons. However the signal to nois...

New computational techniques could help researchers pinpoint anatomical source of seizures

For the third of all epilepsy patients who don’t respond to medication, an alternative is to locate the small cluster of neurons that act as the seed of a seizure’s aberrant electrical activity and surgically remove it. Unfortunately, such surgeries often fail to bring any relief. The ability to reliably pinpoint the anatomical source of seizures, different for each patient, remains elusive. Researchers at the University of Pennsylvania’s School of Engineering and Applied Science and Perelman School of Medicine are looking for ways to refine this process by looking at networks of electrical activity in the brain just prior to the onset of a seizure. Using brain data crowdsourced from 22 epilepsy patients with implanted electrodes, the researchers have developed a series o...

Status Epilepticus Redefined.

Status Epilepticus is a prolonged seizure that can have dire consequences for the individual who is suffering it. There has been some confusion as to what timeframe or length of seizure is considered an SE event. Emergency Treatment has traditionally been started at about 5 minutes of seizure duration and SE declared at about 30 minutes. “The problem has been that you had these two definitions floating around,” that included 5 minutes or 30 minutes, depending on whether you were talking about when to treat or consequences, said study author Shlomo Shinnar, MD, PhD, professor, neurology, pediatrics and epidemiology and population health, and director, Comprehensive Epilepsy Management Center, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

New Wearable EEG!

Researchers have developed a wearable electroencephalogram (EEG) device that can detect and record seizure activity in epilepsy patients in the outpatient setting, they reported on Monday at the annual meeting of the American Epilepsy Society in Philadelphia. The so-called EEG Patch, a small, waterproof, scalp-mounted device, was designed to help patients more accurately track their seizures, Mark Lehmkuhle, PhD, a research assistant professor in neurosurgery at the University of Utah School of Medicine in Salt Lake City, who presented the findings at the meeting, told the Neurology Today Conference Reporter ahead of the session.   The EEG Patch is designed to be fixed to a part of the patient’s scalp where seizures are known to originate based on EEG recorded in-hospital during a traditio...

Study sheds light on postictal generalised EEG suppression

A study in Neurology finds postictal generalised EEG suppression (PGES) to be more common in patients who are not given prompt oxygen, and after type 1 generalised convulsive seizures (GCS). The analysis of video-EEG recordings of 417 patients with drug-refractory epilepsy from the prospective REPO2MSE study shows that PGES was 14.2 times more likely to occur if oxygen was not given early (during seizure or within 5 seconds of its end). This association was independent of confounding variables, implying that prompt oxygen administration could be a powerful preventive tool. However, editorialists Orrin Devinsky (NYU School of Medicine, New York, USA) and Lina Nashef (King’s College Hospital, London, UK) caution that the study could not control for “whether oxygen was key, or the accompanyin...

Autism-epilepsy connection explored in four studies

Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies suggest that epileptic seizures impair the neural pathways needed for socialization, but the details of this process remain unclear. Four studies presented at the American Epilepsy Society’s recent Annual Meeting delve deeper into this relationship, revealing biological mechanisms and clinical findings that could help advance treatments for patients with both disorders. Jennifer Avallone, DO, and colleagues retrospectively examined the video EEG findings and clinical records of 53 children and adults diagnosed with both epilepsy and ASD. Th...

New research could revolutionize global diagnostic procedures for epilepsy

Pioneering new research by the University of Exeter could revolutionize global diagnostic procedures for one of the most common forms of epilepsy. Scientists from Exeter have investigated using mathematical modelling to assess susceptibility to idiopathic generalised epilepsy (IGE) by analysing electrical activity of the brain while the patient is in a resting state. Current diagnosis practices typically observe electrical activities associated with seizures in a clinical environment. The ground-breaking research has revealed differences in the way that distant regions of the brain connect with each other and how these differences may lead to the generation of seizures in people with idiopathic generalized epilepsies (IGE). By using computer algorithms and mathematical models, the research...

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