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Diabetes

Epilepsy tied to severe hypoglycemia in type 2 diabetes

Adults with type 2 diabetes have an increased risk for epilepsy, especially in the presence of severe hypoglycemia, compared with adults without type 2 diabetes, according to findings published in Diabetes Research & Clinical Practice.   Chung-Yi Lu, PhD, professor in the department and graduate Institute of Public Health at the College of Medicine, National Cheng Kung University in Taiwan, and colleagues evaluated data from Taiwan’s National Health Insurance claims on 751,792 adults with type 2 diabetes (mean age, 59.51 years; 51% women) and 824,253 matched controls (mean age, 59.47 years; 51% women) identified between 2002 and 2003 to determine the potential link between type 2 diabetes and epilepsy and the role that severe hypoglycemia may play in the relationship. Participants...

New scoring system may help predict memory and thinking problems in elderly people

Researchers have developed a new scoring system to help determine which elderly people may be at a higher risk of developing the memory and thinking problems that can lead to dementia, according to a new study published in the March 18, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. “Our goal is to identify memory issues at the earliest possible stages,” said study author Ronald C. Petersen, MD, PhD, of Mayo Clinic in Rochester, Minn., and a member of the American Academy of Neurology. “Understanding what factors can help us predict who will develop this initial stage of memory and thinking problems, called mild cognitive impairment (MCI), is crucial, because people with MCI have an increased risk of developing dementia.”...

Nasal Spray for Memory?

Insulin Detemir Nasal Spray May Improve Memory in Alzheimer’s Insulin detemir delivered via nasal spray may improve working memory in patients with mild cognitive impairment or Alzheimer’s disease, according to data from a pilot study published in the Journal of Alzheimer’s Disease. Previous studies have demonstrated the potential benefits of intranasal insulin in adults with mild cognitive impairment or Alzheimer’s disease, but no other research has evaluated the effects of intranasally administered insulin detemir, which is a long-lasting insulin analog. For this study, the researchers assigned 60 adults diagnosed with mild cognitive impairment or mild to moderate Alzheimer’s disease to receive placebo (n=20), 20 IU of insulin detemir (n=21) or 40 IU of insu...

Epilepsy and Depression and Anxiety

Comorbid Conditions in Epilepsy The proper treatment of epilepsy requires eliminating seizures as much as possible without incurring intolerable side effects. Furthermore, identifying and treating comorbid conditions, both psychiatric and somatic, has recently emerged as an important priority. In my team’s recent research, we identified somatic and psychiatric comorbid conditions in 50% of women and 43% of men in a population of 6621 people with epilepsy.[1] The top comorbid conditions for women and men with epilepsy were a psychiatric diagnosis, hyperlipidemia, hypertension, asthma, diabetes, headache, and anemia.[1] A spate of articles emphasizing the importance of epilepsy-related comorbid conditions recently appeared in Epilepsy and Behavior. Asato and colleagues[2] wrote, “...

AAN: People who develop diabetes in middle age are more likely to have brain cell loss in old age

People who develop diabetes and high blood pressure in middle age are more likely to have brain cell loss and other damage to the brain, as well as problems with memory and thinking skills, than people who never have diabetes or high blood pressure or who develop it in old age, according to a new study published in the March 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. Middle age was defined as age 40 to 64 and old age as age 65 and older. “Potentially, if we can prevent or control diabetes and high blood pressure in middle age, we can prevent or delay the brain damage that occurs decades later and leads to memory and thinking problems and dementia,” said study author Rosebud O. Roberts, MB, ChB, MS, of the Mayo Clinic in Roche...

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