Although it’s been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer’s disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, a team of researchers reveals a mechanism that can explain how even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models. A better understanding of this new mechanism may lead to future strategies to reduce cognitive deficits in Alzheimer’s disease and other conditions associated with seizures, such as epilepsy.
The latest study on hormone therapy and Alzheimer’s disease shows no relationship between taking the drugs and whether you may develop the disease years later.
UT Southwestern Medical Center has joined a consortium of seven leading universities to develop new technologies to improve memory in people with traumatic brain injury, mild cognitive impairment, epilepsy, and Alzheimer’s disease. Specifically, UT Southwestern is part of a study with the goal of developing an implantable neural monitoring and stimulation system by the end of 2018 that would treat memory loss.
Experts at the University of Pittsburgh School of Medicine are leading the second arm of a clinical trial using gene therapy to relieve the symptoms of tremor and mobility impairment in patients with Parkinson’s disease. The technique shows promise in prolonging the effectiveness of levo-dopa, the mainstay treatment for the progressive neurodegenerative condition, by increasing production of a key enzyme essential to convert the drug into the neurotransmitter dopamine.
Too many tests at the doctor’s office could cost you more than just dollars. In addition to the huge hit to your wallet, there’s also the potential harm of false positives, and just because a test has traditionally been done for a condition doesn’t mean it’s the best way to treat it. U-M neurologist Brian Callaghan, M.D., M.S., is helping lead a national push to determine what neurologic tests or services are performed more than they should be. It comes out of a campaign called Choosing Wisely, an initiative of the ABIM Foundation, which works with more than 70 medical specialty societies to encourage conversations between clinicians and patients about avoiding wasteful or unnecessary medical tests, treatments and procedures. Each society, including the American Aca...