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Valproic Acid Concentration Drops With Ketogenic Diet

For patients with epilepsy, anti-epileptic drug serum concentrations remain stable during the ketogenic diet, apart from those of valproic acid, according to a study published online June 18 in the Journal of Clinical Pharmacy and Therapeutics. Changes in serum concentrations of other anti-epileptic drugs not found to be significant. For patients with epilepsy, anti-epileptic drug serum concentrations remain stable during the ketogenic diet (KD), apart from those of valproic acid, according to a study published online June 18 in the Journal of Clinical Pharmacy and Therapeutics.

Epilepsy and natural treatments: Can they help?

Epilepsy is a disease that disrupts the electrical activity of the nervous system, causing seizures. More than 65 million people in the world have epilepsy. 1 in 26 Americans will develop the disease during their lives. Children are the group most frequently diagnosed with new cases of epilepsy. In the United States, 300,000 children under 14 are affected by the condition. Some may outgrow the disorder, but most will not. The number of senior citizens with epilepsy is also 300,000. People with epilepsy have a range of treatment options, including alternative therapies. The illness is a complex condition, however, and all alternative treatment options must be looked at carefully, to ensure they are effective. Causes of epilepsy Epilepsy is a complex disease that can disrupt the electrical a...

Noninvasive Deep Brain Stimulation Can Become Reality, Mouse Study Shows

Researchers have, for the first time, showed that it is possible to stimulate structures deep within the brain without the need for implanted electrodes — opening the possibility that epilepsy patients could receive deep brain stimulation in a noninvasive manner. The method applies scalp electrodes that send two currents into the brain. Brain cells only become stimulated in the spot where the two currents intersect, making it possible to easily change the exact size and location of the treatment.

Secret of Epilepsy Discovered in Jerusalem?

Unable to figure out what causes the neurological disorder, the scientists thought to ask: What causes normal people (or lab animals) not to have it? Epileptic seizures are caused by abnormal activity in our brain. We know that. Attacks can be unprovoked or can be the result from a tendency that is created, for instance, by head trauma or exposure to certain stimuli. We know that too. We don’t know, however, is why some people are prone to epilepsy and some are not.

In a first, marijuana substance reduces seizures for some epilepsy patients in clinical trial

For the first time, scientists have demonstrated that a component of cannabis reduces seizures in children with a rare form of epilepsy, marking a significant step in efforts to use marijuana and its derivatives to treat serious medical conditions.

EpiFinder, Inc. Announces Analytics Software to Improve Epilepsy Diagnosis and Seizure Events

EpiFinder, Inc., is pleased to announce its proprietary clinical decision analytics software to improve epilepsy syndrome diagnosis and seizure event management at the point-of-care. The early-stage Arizona company provides intelligent analytics and support to doctors, neurologists and healthcare professionals (Nurse Practitioners, Physician Assistants, and more) to enhance the lives of patients with epilepsy.

Lawmakers push legislation to provide epilepsy treatment nationwide

A controversial treatment for children with severe epilepsy could become legal nationwide. The treatment uses oil derived from Marijuana. While the treatment is legal in 44 states across the country, the treatment is still a challenge for many to access. Charlotte Figi, 10, is a happy and healthy third-grader from Colorado Springs. It’s a sight, mother, Paige Figi says she thought she’d never witness. Five and a half years ago, she was preparing to say goodbye.

Stem Cell Therapy Shows Potential in Treating Medication-resistant Epilepsy Patients

Stem cell therapy may be a safe and promising treatment option for epilepsy patients who are resistant to antiepileptic drugs, according to new research. The study, “Treatment of refractory epilepsy patients with autologous mesenchymal stem cells reduces seizure frequency: An open label study,” was published  in the journal Advances in Medical Sciences. Stem cell therapy consists of using stem cells (immature cells that can become any other cell type in the body) to replace faulty cells and treat patients with a given disease. Many approaches include using the patient’s own stem cells (autologous stem cells), collected from specific organs, such as the bone marrow. This method prevents future complications such as rejection by the body or a response from the person’s immune system. The Pha...

New UTHealth study focuses on treatment for epilepsy caused by tuberous sclerosis

A clinical trial of a drug that researchers hope can prevent or delay the onset of epilepsy in children with tuberous sclerosis has begun at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). The Houston site, one of just seven in the country, is led by Mary K. Koenig, M.D., associate professor and Endowed Chair of Mitochondrial Medicine in the Division of Neurology of the Department of Pediatrics at McGovern Medical School at UTHealth. “It could potentially be a game-changer for epilepsy in general as it is the first trial ever aimed at preventing seizures from developing in a vulnerable population,” Koenig said. Tuberous sclerosis complex (TSC) is a genetic disorder that causes tumors to form in many different organs, including the...

Members of Congress and Senate in Support of the New CBD Bill

 Known as the Therapeutic Hemp Medical Access Act, a bipartisan bill introduced this week seeks to ensure unrestricted access to specific strains high in CBD for individuals battling intractable epilepsy. Requesting an exemption from the Controlled Substance Act (CSA) for “strains of therapeutic hemp” known to be high in Cannabidiol (CBD), the bill was announced and endorsed by nine state senators on Tuesday.

Pinpointing where seizures are coming from, by looking between the seizures

A computational approach developed at Boston Children’s Hospital, described in the journal Neurosurgery, published online May 2, 2017, could enable more patients with epilepsy to benefit from surgery when medications do not help. The approach streamlines the seizure monitoring process required for surgical planning, making surgery a more feasible and less risky option for patients. Currently, for some patients, pinpointing the diseased brain areas where their seizures originate requires invasive surgery to place grids of electrodes on the brain’s surface. This is followed by long-term electroencephalography (EEG) monitoring—typically for a week—while doctors wait for a seizure to happen. Then, patients must undergo a second brain operation to remove the diseased tissue. The new...

Man’s best friend: Evolutionary history of dogs could shed light on cancer, epilepsy in both species

An evolutionary tree of more than 161 dog breeds has been mapped out by geneticists, showing which types are closely related to each other. The research will be of obvious interest to dog owners but it is hoped it will shed light on the causes of diseases that affect both dogs and humans, including epilepsy.

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