A technique called MRI-guided laser interstitial thermal therapy (MgLiTT) may be a potential treatment for epilepsy patients, according to a recent review. Researchers say that MgLiTT may be a particularly viable option for patients whose seizures are caused by tumor-like bodies affecting the hypothalamus, which are difficult to treat with traditional surgery.
Researchers studied the medical records of patients with drug-resistant focal epilepsy who underwent surgery for the disorder at the age of 50 or older and found that the treatment was as effective as it was for patients younger than 50. However, there was a higher risk of complications from the procedure.
For patients that find their seizures difficult to manage on medications, other treatment options such as diet, devices or surgery may be beneficial. Dr. Amy Crepeau, neurologist at Mayo Clinic in Arizona, discusses the evaluation of patients with epilepsy using brain mapping technology.
In a pair of studies, scientists at the National Institutes of Health explored how the human brain stores and retrieves memories. One study suggests that the brain etches each memory into unique firing patterns of individual neurons. Meanwhile, the second study The studies were led by Kareem Zaghloul, M.D., Ph.D., a neurosurgeon-researcher at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS). Persons with drug resistant epilepsy in protocols studying surgical resection of their seizure focus at the NIH’s Clinical Center enrolled in this study. To help locate the source of the seizures, Dr. Zaghloul’s team surgically implanted a grid of electrodes into the patients’ brains and monitored electrical activity for several days.
There are important, long-term gains from hastening the processes around surgical interventions against epilepsy – before the disease has had too much negative impact on brain functions and patients’ lives. These are some of the findings of a thesis for which more than 500 patients were studied and followed up.
Mutations in a gene called SCN2A have opposite effects in autism and in epilepsy. The divergence makes the gene an attractive candidate for research, suggest unpublished results presented today at the 2016 Society for Neuroscience annual meeting in San Diego.
New research from the University of Liverpool, published in the journal Brain, has highlighted the potential reasons why many patients with severe epilepsy still continue to experience seizures even after surgery.
Research has shown that surgery can provide important benefits for patients with epilepsy. Now a new study finds that it is also cost-effective. In a study of 207 patients with epilepsy who were treated at 15 different centers in France, the proportion of patients who were completely seizure-free during the last 12 months was 69 percent among patients who underwent surgery and 12 percent among patients who received continued medical care during the second year, and it was respectively 77 percent and 21 percent during the fifth year. Direct costs became significantly lower in the surgical group during the third year after surgery, as a result of less antiepileptic drug use. “Surgery became cost-effective between nine and 10 years after surgery and even earlier if indirect costs were t...