Researchers recently published an article in The Lancet Neurology discussing the difficulties facing seizure detection in patients with epilepsy. Epilepsy is a neurological disorder that is characterised by short repetitive epileptic seizures. These seizures can be harmful to the individual depending on the circumstances in which they occur, such as a seizure while driving. This disorder is set apart from other neurological disorders since there is a broad range of different physiological changes that can cause it, leading to a large variation in symptoms and making it difficult to treat. While 70% of sufferers can be treated with pharmacological agents, 30% have no reliable anti-epileptic drugs that are effective for their particular type of epilepsy.
University of Cincinnati Academic Health Center Research scientist Jianxiong Jiang, PhD, doesn’t just want to treat acquired epilepsy…he hopes to prevent it. “Epilepsy is a common neurological condition that afflicts nearly three million Americans and 50 to 60 million people globally. The disease is featured by epileptic seizures due to unusual hypersynchronization and hyperexcitability of a group of brain neurons,” says Jiang, an assistant professor at the University of Cincinnati (UC) James L. Winkle College of Pharmacy.
Learning techniques to help manage stress may help people with epilepsy reduce how often they have seizures, according to a study published in the February 14, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. “Despite all the advances we have made with new drugs for epilepsy, at least one-third of people continue to have seizures, so new options are greatly needed,” said study author Sheryl R. Haut, MD, of Montefiore Medical Center and the Albert Einstein College of Medicine in the Bronx, NY, and member of the American Academy of Neurology. “Since stress is the most common seizure trigger reported by patients, research into reducing stress could be valuable.” The study involved people with seizures that did no...
An infant’s scores on the so-called Apgar scale can predict the risk of a later diagnosis of cerebral palsy or epilepsy. The risk rises with decreasing Apgar score, but even slightly lowered scores can be linked to a higher risk of these diagnoses, according to an extensive observational study by researchers at Karolinska Institutet in Sweden published in the esteemed journal The BMJ.
Brain training devised by a Brighton clinical researcher can cut the number and frequency of epileptic seizures in patients who have not responded to drug treatment. Details of the groundbreaking research have been published in The Lancet and Cell Press journal Ebiomedicine. One in 100 people suffer with epilepsy – 50 million people worldwide – with about 30 per cent of them apparently unable to benefit from drugs to manage the condition. About half of those taking part in clinical trials reported that the technique reduced seizures by 50 per cent or more. It was invented by Yoko Nagai, Wellcome Trust Research Fellow at the Brighton and Sussex Medical School, run jointly by Brighton University and Sussex University. The technique is seen as an alternative...
he largest-ever neuroimaging study of people with epilepsy shows that epilepsy involves more widespread physical differences than previously assumed Epilepsy, a disorder in which nerve cell activity in the brain is disturbed, is linked to brain volume and thickness differences, according to a study. Epilepsy is a neurological disorder that affects 0.6-1.5% of the global population, comprising many different syndromes and conditions, and defined by a tendency for seizures. The research was led by UCL and the Keck School of Medicine of USC. The largest-ever neuroimaging study of people with epilepsy shows that epilepsy involves more widespread physical differences than previously assumed, even in types of epilepsy that are typically considered to be more benign if...
A complex partial seizure is a type of seizure that arises in one lobe of the brain, rather than the whole brain. The seizure affects people’s awareness and may cause them to lose consciousness. Complex partial seizures are now more commonly referred to as focal onset impaired awareness seizures or focal impaired awareness seizures.
Implanted electrodes reveal long-term patterns of seizure risk. University of California San Francisco neurologists have discovered monthly cycles of brain activity linked to seizures in patients with epilepsy. The finding, published online January 8 in Nature Communications, suggests it may soon be possible for clinicians to identify when patients are at highest risk for seizures, allowing patients to plan around these brief but potentially dangerous events.
Several new Australian-developed medicines showing promise treating childhood epilepsy, stroke and autoimmune diseases have emerged from an unusual source: the fangs of venomous creatures. Big pharmaceutical companies are excited by results showing these new venom-drugs are often superior to man-made drugs, and they are starting to pour money into research.
The team plans to continue using its improved organoids to better understand human brain development and to learn more about autism spectrum disorders, epilepsy and other neurological conditions. UCLA researchers have developed an improved technique for creating simplified human brain tissue from stem cells. Because these so-called “mini brain organoids” mimic human brains in how they grow and develop, they’re vital to studying complex neurological diseases. In a study published in the journal Cell Reports, the researchers used the organoids to better understand how Zika infects and damages fetal brain tissue, which enabled them to identify drugs that could prevent the virus’s damaging effects.
Febrile seizures (febrile convulsions) are fits (sic – Seizures) that can happen when a child has fever. They are the most common type of seizure in paediatric age group. They most commonly happen between the ages of 6 months to 6 years. The cumulative incidence is estimated about 5-7% and the peak incidence is noted at 18 months of age. It can be frightening and distressing to see your child having a seizure (fits), particularly if it is the first episode they are witnessing.
While a number of studies have suggested that marijuana may be effective for reducing seizures, new research cautions that potent and synthetic forms of the drug have the opposite effect. Researchers from the University of Tsukuba in Japan found that natural tetrahydrocannabinol (THC) – the psychoactive chemical in marijuana – and the synthetic cannabinoid JWH-018 caused seizures in mice. Study leader Olga Malyshevskaya and colleagues say that their findings – which are published in the journal Scientific Reports – should serve as a “public alert” to the potential harms caused by high-potency and synthetic marijuana.