Several new Australian-developed medicines showing promise treating childhood epilepsy, stroke and autoimmune diseases have emerged from an unusual source: the fangs of venomous creatures. Big pharmaceutical companies are excited by results showing these new venom-drugs are often superior to man-made drugs, and they are starting to pour money into research.
The team plans to continue using its improved organoids to better understand human brain development and to learn more about autism spectrum disorders, epilepsy and other neurological conditions. UCLA researchers have developed an improved technique for creating simplified human brain tissue from stem cells. Because these so-called “mini brain organoids” mimic human brains in how they grow and develop, they’re vital to studying complex neurological diseases. In a study published in the journal Cell Reports, the researchers used the organoids to better understand how Zika infects and damages fetal brain tissue, which enabled them to identify drugs that could prevent the virus’s damaging effects.
Febrile seizures (febrile convulsions) are fits (sic – Seizures) that can happen when a child has fever. They are the most common type of seizure in paediatric age group. They most commonly happen between the ages of 6 months to 6 years. The cumulative incidence is estimated about 5-7% and the peak incidence is noted at 18 months of age. It can be frightening and distressing to see your child having a seizure (fits), particularly if it is the first episode they are witnessing.
While a number of studies have suggested that marijuana may be effective for reducing seizures, new research cautions that potent and synthetic forms of the drug have the opposite effect. Researchers from the University of Tsukuba in Japan found that natural tetrahydrocannabinol (THC) – the psychoactive chemical in marijuana – and the synthetic cannabinoid JWH-018 caused seizures in mice. Study leader Olga Malyshevskaya and colleagues say that their findings – which are published in the journal Scientific Reports – should serve as a “public alert” to the potential harms caused by high-potency and synthetic marijuana.
When people see an image of a person they recognize—the famous tennis player Roger Federer or actress Halle Berry, for instance—particular cells light up in the brain. Now, researchers reporting in Current Biology on September 21 have found that those cells light up even when a person sees a familiar face or object but fails to notice it. The only difference in that case is that the neural activity is weaker and delayed in comparison to what happens when an observer consciously registers and can recall having seen a particular image.
Fever is the most common trigger for seizures in children between 5 months and 6 years of age. But the underlying cause is not always clear. Now in a study published in the journal Epilepsy Research, Jing-Qiong (Katty) Kang, M.D., Ph.D., and colleagues show in a genetically altered mouse model that elevated body temperature alone can increase vulnerability to febrile seizures even in the absence of infection or inflammation.
Some drugs used to treat epilepsy harm children who are exposed to them in the womb or through breast milk, a new analysis of the literature suggests1. The drug valproate is particularly risky, boosting the likelihood of autism and other developmental problems up to 17-fold. The study is the first to compare the relative risks of taking various epilepsy drugs during pregnancy. Some of these medications are also used to treat bipolar disorder and migraines.
you know what a grand mal seizure is? I found out when I was eight years old. I also found out how it felt after having one…a mouth being full of swollen tongue, the taste of blood, and the feeling of being underwater with a throbbing headache. As with most epileptics, doctors have no idea why I have it or what caused it. Mine is not genetic; it may have resulted from one of the many times I thwacked my head as a kid. I liked to hang upside-down on the monkey bars a lot. No surprise that my stampeding hippo brand of grace emerged early, and that I frequently fell from exactly that upside-down position.
Did you know that seizures are more likely to develop in older adults? Learn to recognize the signs of seizures and how you can help. Epilepsy is a broad term used for a brain disorder that causes seizures. In the United States, 2.4 million adults aged 18 years or older have active epilepsy.1,2 About 1% of adults 65 years of age and older have active epilepsy, which is about 447,000 people.1,2 That’s about the size of Corpus Christi, TX. With the aging of the population, we can expect to see greater numbers of people with epilepsy. Epilepsy is more likely to develop in older adults rather than younger adults because as people age, the risk of seizures and epilepsy rises.3,4 Some older adults may have lived with epilepsy throughout their lives, but others might develop epilepsy later in lif...
Scientists are increasingly appreciating estrogen’s role in brain health. Now for the first time, production of estrogen in the brain has been directly linked to the presence of docosahexaenoic acid (DHA). DHA is found in abundance in fish oils and is also synthesized from alpha-linolenic acid, an omega-3 fatty acid found in some vegetable-based oils.
Epilepsy, a brain disorder leading to recurring seizures, has garnered increased public health focus because persons with epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment advances, public awareness programs, and expanded rights for persons with disabilities (1,2). For almost all states, epilepsy prevalence estimates do not exist. CDC used national data sources including the 2015 National Health Interview Survey (NHIS) for adults (aged ≥18 years), the 2011–2012 National Survey of Children’s Health (NSCH), and the 2015 Current Population Survey data, describing 2014 income levels, to estimate prevalent cases of active epilepsy, overall and by state, to provide information for state public health planning. In 2015, 1.2% of the U.S. populatio...
Childhood absence epilepsy (CAE), a syndrome that occurs in 1 out of 1000 children, is one of the most common types of early childhood (first decade) seizures. A classic CAE scenario may be that of a little girl who has just started kindergarten and has periods of “blanking out” every day. Her teacher calls out her name, but she does not respond. She sometimes blinks her eyes a few times and is back to “normal” in about 20 seconds. The teacher alerts the parents, who then make an appointment to see the pediatrician. Typically, the parents report never noticing these episodes at home.