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Stereo EEG provides a deep, detailed map of the brain as physicians evaluate patients for the surgical treatment of epilepsy.

For patients that find their seizures difficult to manage on medications, other treatment options such as diet, devices or surgery may be beneficial. Dr. Amy Crepeau, neurologist at Mayo Clinic in Arizona, discusses the evaluation of patients with epilepsy using brain mapping technology.

INTERVIEW: Distinguishing Epilepsy From its Imitators with EEG

In this interview, Dr. Andrew N. Wilner, MD, interviews Dr. Joseph F. Drazkowski, MD who is involved with the American Academy of Neurology developing courses for neurologists, for increasing proficiency in EEG and EEG video. Excerpt from Medscape:

Optical technologies could lead to novel treatments for neurological diseases

Optical technologies previously used to look at the stars in the sky will be miniaturized to look inside the brain, and could lead to new treatments for neurological diseases. The technologies once used to make corrections to space telescopes, along with new lasers, will help answer a fundamental question, according to Prakash Kara, Ph.D., a researcher at the Medical University of South Carolina: “Is there a universal microcircuit that is repeated everywhere in the brain with regard to how neurons communicate with blood vessels?” Kara is part of a team at MUSC that was awarded a $4 million grant from the National Science Foundation through its Experimental Program to Stimulate Competitive Research (EPSCoR). The grant will fund collaborative research between MUSC and the Univers...

New Wearable EEG!

Researchers have developed a wearable electroencephalogram (EEG) device that can detect and record seizure activity in epilepsy patients in the outpatient setting, they reported on Monday at the annual meeting of the American Epilepsy Society in Philadelphia. The so-called EEG Patch, a small, waterproof, scalp-mounted device, was designed to help patients more accurately track their seizures, Mark Lehmkuhle, PhD, a research assistant professor in neurosurgery at the University of Utah School of Medicine in Salt Lake City, who presented the findings at the meeting, told the Neurology Today Conference Reporter ahead of the session.   The EEG Patch is designed to be fixed to a part of the patient’s scalp where seizures are known to originate based on EEG recorded in-hospital during a traditio...

Study sheds light on postictal generalised EEG suppression

A study in Neurology finds postictal generalised EEG suppression (PGES) to be more common in patients who are not given prompt oxygen, and after type 1 generalised convulsive seizures (GCS). The analysis of video-EEG recordings of 417 patients with drug-refractory epilepsy from the prospective REPO2MSE study shows that PGES was 14.2 times more likely to occur if oxygen was not given early (during seizure or within 5 seconds of its end). This association was independent of confounding variables, implying that prompt oxygen administration could be a powerful preventive tool. However, editorialists Orrin Devinsky (NYU School of Medicine, New York, USA) and Lina Nashef (King’s College Hospital, London, UK) caution that the study could not control for “whether oxygen was key, or the accompanyin...

SPECT scan measures brain activity during seizures

Loyola University Medical Center is offering epileptic patients an imaging scan that records brain activity during seizures. The scan is called single photon emission computed tomography (SPECT). It highlights the hotspot in the brain where seizures originate. It’s used in patients who are potential candidates for surgery to remove the portion of the brain responsible for seizures, known as the epileptogenic zone. Surgery is an option for patients who do not respond to medications, or cannot tolerate the side effects. Surgery is considered only when the area to be removed is not responsible for critical functions. A SPECT scan measures blood flow, which increases in the area of the epileptogenic zone during seizures. Prior to undergoing the scan, the patient is admitted to the Epilep...

New research could revolutionize global diagnostic procedures for epilepsy

Pioneering new research by the University of Exeter could revolutionize global diagnostic procedures for one of the most common forms of epilepsy. Scientists from Exeter have investigated using mathematical modelling to assess susceptibility to idiopathic generalised epilepsy (IGE) by analysing electrical activity of the brain while the patient is in a resting state. Current diagnosis practices typically observe electrical activities associated with seizures in a clinical environment. The ground-breaking research has revealed differences in the way that distant regions of the brain connect with each other and how these differences may lead to the generation of seizures in people with idiopathic generalized epilepsies (IGE). By using computer algorithms and mathematical models, the research...

PRESS RELEASE: Epilepsy Research Opens a Window to the Brain

Cool Science and New Discoveries Highlighted During Epilepsy Awareness Month Newswise — West Hartford, Conn., November 5, 2014 — Rapidly emerging technologies, novel imaging techniques, the development of new therapies and new genes, have given researchers and clinicians an extraordinary ability to explore the brain at the cellular, genetic and neural levels. While current epilepsy research may seem like it’s ripped from the pages of a science fiction novel, it’s real—and even pretty cool. Epilepsy provides researchers with unparalleled avenues to discover how the brain is structured and how it functions: a true ‘window on the brain.’ In recognition of Epilepsy Awareness Month the American Epilepsy Society (AES) is highlighting just a few of the groundbreaking scientific developments...

VIDEO: Robotic System Implants Electrodes in the Brain

UAMS is only the 5th center in the country to get a robotic system to implant electrodes in the brain to identify the source of seizures. The system is called ROSA, and it cuts the time to implant the electrodes down from 10 hours to less than 3. It also eliminates human error and increases accuracy. This is life-changing technology for many where MRI does not show a tumor or lesion on the brain, when electrodes are needed to find the source of the seizures. “So the old way of putting electrodes in for monitoring seizures when you don’t have an actual lesion to see on an MRI that you can remove you have to put electrodes in to record electrically,” explains Dr. Serletis.

SEEG an Option for Difficult-to-Localize Epilepsy in Kids

(via Medscape) At least half of a small group of children and adolescents with difficult-to-localize refractory focal epilepsy was rendered seizure-free or much improved with stereoelectroencephalography (SEEG) methods, new research shows. The procedure is also associated with minimal blood loss and significantly less morbidity than are older mapping techniques. “The patients we studied are not the usual group of patients with seizures that are easy to localize and chances of them becoming seizure-free are over 80%,” Jorge Gonzalez-Martinez, MD, Epilepsy Center, Cleveland Clinic Cleveland, Ohio, told Medscape Medical News. “We are talking about patients whose seizures are really difficult to localize, they have failed medication and even surgery so they are really a diffi...

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