Today I received some devastating news. I received a Facebook Message from someone I know: “Chuck, My son died of epilepsy on Mother’s Day. He may have had abdominal form since middle school. How can we raise awareness for those with epilepsy and cyclic vomiting? He left some acoustic guitar music he played despite repeated seizures and memory loss.” From a father and a doctor. Many people may not be aware that there is a water born ameba (Yes, even in the U.S.) that eats away the brain tissue and can result in seizures and other illness.
Known as the Therapeutic Hemp Medical Access Act, a bipartisan bill introduced this week seeks to ensure unrestricted access to specific strains high in CBD for individuals battling intractable epilepsy. Requesting an exemption from the Controlled Substance Act (CSA) for “strains of therapeutic hemp” known to be high in Cannabidiol (CBD), the bill was announced and endorsed by nine state senators on Tuesday.
Tiny, 3-D clusters of human brain cells grown in a petri dish are providing hints about the origins of disorders like autism and epilepsy. An experiment using these cell clusters — which are only about the size of the head of a pin — found that a genetic mutation associated with both autism and epilepsy kept developing cells from migrating normally from one cluster of brain cells to another, researchers report in the journal Nature.
Babies born to severely obese, or grade III obesity, was associated with an 82 per cent increased risk of epilepsy. A study of almost 1.5 million children has found the risk of epilepsy almost doubled among those born to severely obese mothers. Being overweight during the first trimester of pregnancy has been linked to an increased risk of childhood epilepsy. A Swedish study of almost 1.5 million babies found the risk of epilepsy almost doubled from normal-weight women to very severely obese women. Epilepsy disrupts the normal electrochemical activity of the brain resulting seizures. The cause of this debilitating and often hard-to-treat condition is poorly understood. With obesity on the rise, there is growing concern about the long-term neurological effects of children expose...
A new study published in Epilepsia found that although most newly diagnosed cases of epilepsy in older adults are treated appropriately with monotherapy, only half of those patients receive treatment within the recommended time frame, and a substantial portion were prescribed older antiepileptic drugs (AEDs) despite recommendations to use newer AEDs in this population.
We have been posting about using Zebrafish to model epilepsy treatment since 2013, and about the potential for treatments to be developed from these models. Fast forward to 2017, and we have a viable treatment in clinical trials! Via News Medical: New drug discovered in zebrafish model of pediatric epilepsy shows promising results in clinical study “Bench-to-bedside” describes research that has progressed from basic science in animal models that has led to therapies used in patients. Now, a study in the journal Brain describes what could be considered a direct “aquarium-to-bedside” approach, taking a drug discovered in a genetic zebrafish model of epilepsy and testing it, with promising results, in a small number of children with the disease. The study was supported...
Over the past few years Sodium Channels have been linked to epilepsy and researchers have focused on this area of research to understand genetic epilepsy. A new study by Northwestern Medicine focused on discovering the genetic causes of irregularities in sodium channels and the potential for regulating them. Via Northwestern Medicine: A new Northwestern Medicine study may help explain why patients with the same epilepsy gene mutation experience different levels of disease severity. The findings, published in the Proceedings of the National Academy of Sciences (PNAS), also reveal new insights into sodium channel regulation and a potential therapeutic target for epilepsy treatment. Christopher Thompson, PhD, research assistant professor of Pharmacology, was the first author of the study, led...
Medtronic plc (NYSE: MDT) announced today that the first procedure using the Visualase(TM) MRI-Guided Laser Ablation System has been performed in the pivotal SLATE (Stereotactic Laser Ablation for Temporal Lobe Epilepsy) clinical trial at Mayo Clinic in Rochester, Minn.
There are important, long-term gains from hastening the processes around surgical interventions against epilepsy – before the disease has had too much negative impact on brain functions and patients’ lives. These are some of the findings of a thesis for which more than 500 patients were studied and followed up.
Scanning a premature infant’s brain shortly after birth to map the location and volume of lesions, small areas of injury in the brain’s white matter, may help doctors better predict whether the baby will have disabilities later.
BETHESDA, Md., Jan. 12, 2017 /PRNewswire-iReach/ — Frontal lobe epilepsy (FLE) comprises 30% of all partial epilepsies; it can masquerade as a primary psychiatric condition or be co-morbid with a psychiatric illness.
A new study shows that older people who followed a Mediterranean diet retained more brain volume over a three-year period than those who did not follow the diet as closely. The study is published in the January 4, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology. But contrary to earlier studies, eating more fish and less meat was not related to changes in the brain.