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Wireless charging system can power up internal body implants

A new system that that wirelessly charges internal implants and wearables could be about to make life easier for patients with conditions such as epilepsy or diabetes.   MagLense is a breakthrough product providing wireless power transfer to internal implants and wearables for more comfortable charging. The system, developed by Cambridge Consultants, provides flexible, efficient and safe wireless power transfer in a simple and user-friendly way.

See these first-of-a-kind views of living human nerve cells

New database could shed light on how people’s brains tick   The human brain is teeming with diversity. By plucking out delicate, live tissue during neurosurgery and then studying the resident cells, researchers have revealed a partial cast of neural characters that give rise to our thoughts, dreams and memories.   So far, researchers with the Allen Institute for Brain Science in Seattle have described the intricate shapes and electrical properties of about 100 nerve cells, or neurons, taken from the brains of 36 patients as they underwent surgery for conditions such as brain tumors or epilepsy. To reach the right spot, surgeons had to remove a small hunk of brain tissue, which is usually discarded as medical waste. In this case, the brain tissue was promptly packed up and sent — ...

Scientists developing a pharmaceutical that stops convulsions

Scientists from RUDN University took an active part in the development of a chemical compound to stop convulsions during epileptic seizures. The results of the study were published in Chirality.   Epilepsy is a chronic neuralgic disease that causes convulsive seizures in humans and other animals. The pathogenesis of this disease is paroxysmal discharges in the nerve cells of the brain that cause convulsions. Anticonvulsants help to stop the epileptic fit. The drug itself is a powder that is dissolved in water and injected into a person experiencing such a seizure.

Star-shaped brain cells orchestrate neural connections

Brains are made of more than a tangled net of neurons. Star-like cells called astrocytes diligently fill in the gaps between neural nets, each wrapping itself around thousands of neuronal connections called synapses. This arrangement gives each individual astrocyte an intricate, sponge-like structure.   New research from Duke University finds that astrocytes are much more than neurons’ entourage. Their unique architecture is also extremely important for regulating the development and function of synapses in the brain.   When they don’t work right, astrocyte dysfunction may underlie neuronal problems observed in devastating diseases like autism, schizophrenia and epilepsy.

In the grip of a drugs crisis – Including Epilepsy Medications

Thousands of people are addicted to a range of drugs originally licensed to treat epilepsy and nerve pain, a Devon doctor warns. Drugs such as gabapentin and pregablin are being prescribed for conditions ranging from anxiety to all sorts of chronic pain, Richard Byng, professor in primary care research at Plymouth University and a General Practitioner (GP) in the city, said.   He is calling for pharmacists, doctors and patients’ groups to work together to reduce the number of prescriptions issued.

A COMPLETE GUIDE TO MEDICAL ALERT SYSTEMS

Aging is a fact of life for everyone. But thanks to advances in medical technology, medications, and tools that make living and workspaces more accessible, people can expect to stay in their homes for far longer today than they used to.   Every year, more than one-fourth of adults 65 and older will take a fall. For those that do, the risk of a repeat fall is doubled.   That doesn’t mean living at home is without its dangers. Every year, more than one-fourth of adults 65 and older will take a fall, according to the Centers for Disease Control. For those that do, the risk of a repeat fall is doubled. One out of five of these falls results in a serious injury to the head or other part of the body, while 95% of hip fractures are caused by falling.

Interim Survey Results Demonstrate Impact on Siblings of Children Suffering from Severe Epilepsy

“In a recently conducted survey by the Dravet Syndrome Foundation, 74 percent of caregivers expressed concerns about the emotional impact on siblings of children with Dravet syndrome, and the interim results from the Sibling Voices Survey are a significant advancement in our understanding of the far-reaching implications that severe childhood epilepsies have on the lives of siblings and loved ones,” said Nicole Villas, President & Scientific Director of the Dravet Syndrome Foundation Board of Directors.  “We are optimistic that the insights gained from the Sibling Voices Survey will assist in the development of tools to help families, and we are grateful for Zogenix’s dedication to addressing the unmet needs of this patient community.”

Mechanism explains how seizures may lead to memory loss

Although it’s been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer’s disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, a team of researchers reveals a mechanism that can explain how even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models. A better understanding of this new mechanism may lead to future strategies to reduce cognitive deficits in Alzheimer’s disease and other conditions associated with seizures, such as epilepsy.

A dietary supplement dampens the brain hyperexcitability seen in seizures or epilepsy

Seizure disorders — including epilepsy — are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability. However, University of Alabama at Birmingham researchers have found that inducing a biochemical alteration in brain proteins via the dietary supplement glucosamine was able to rapidly dampen that pathological hyperexcitability in rat and mouse models. These results, seen in animal models, represent a potentially novel therapeutic target for the treatment of seizure disorders.

Lack of CLOCK protein appears key in severe epilepsy forms

A new study in Neuron focuses on the role that a lack of the protein “CLOCK” plays in several forms of epilepsy. The study provides evidence that excessive excitation of specific brain cells may be due to a lack of CLOCK in the region of the brain that produces the seizures. This effect, researchers found, is stronger during sleep.The finding potentially gives researchers a new way to develop a treatment for some cases of the most severe cases of the disabling disorder, said corresponding author Dr. Judy Liu, a new Assistant Professor of Neurology at Brown University. Because the study directly implicates a specific protein pathway in a specific part of a patient’s brain, Liu said a strategy for further research could be to deliver a drug that compensates for the lack of ...

Better mini brains could help scientists identify treatments for Zika-related brain damage

The team plans to continue using its improved organoids to better understand human brain development and to learn more about autism spectrum disorders, epilepsy and other neurological conditions.   UCLA researchers have developed an improved technique for creating simplified human brain tissue from stem cells. Because these so-called “mini brain organoids” mimic human brains in how they grow and develop, they’re vital to studying complex neurological diseases.   In a study published in the journal Cell Reports, the researchers used the organoids to better understand how Zika infects and damages fetal brain tissue, which enabled them to identify drugs that could prevent the virus’s damaging effects.

SenTiva Approved for Treatment of Epilepsy

Device billed as smallest, lightest responsive therapy for drug-resistant epilepsy   The SenTiva implantable generator and Vagus Nerve Stimulation (VNS) Therapy Programming System (LivaNova USA) have received FDA approval for the treatment of patients with drug-resistant epilepsy.   SenTiva is the smallest and lightest responsive therapy for epilepsy, LivaNova says. The new VNS Therapy Programming System features a wireless wand and new user interface on a small tablet. Together, the components offer patients with drug-resistant epilepsy a physician-directed customizable therapy with smart technology and proven results to reduce the number of seizures, lessen the duration of seizures, and enable a faster recovery, LivaNova says.

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