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Surgery in Older Patients with Drug-resistant Focal Epilepsy Still Effective, Study Finds

Researchers studied the medical records of patients with drug-resistant focal epilepsy who underwent surgery for the disorder at the age of 50 or older and found that the treatment was as effective as it was for patients younger than 50. However, there was a higher risk of complications from the procedure.

Valproic Acid Concentration Drops With Ketogenic Diet

For patients with epilepsy, anti-epileptic drug serum concentrations remain stable during the ketogenic diet, apart from those of valproic acid, according to a study published online June 18 in the Journal of Clinical Pharmacy and Therapeutics. Changes in serum concentrations of other anti-epileptic drugs not found to be significant. For patients with epilepsy, anti-epileptic drug serum concentrations remain stable during the ketogenic diet (KD), apart from those of valproic acid, according to a study published online June 18 in the Journal of Clinical Pharmacy and Therapeutics.

Epilepsy Patients More Likely to Have Been Abused as Children, Study Finds

Childhood abuse, both sexual and emotional, is more frequently reported in epilepsy patients when compared to the general population, according to the results of a German study. These findings are in agreement with previous studies and highlight the need for additional vigilance on the familiar settings of children with epilepsy.

Epilepsy and natural treatments: Can they help?

Epilepsy is a disease that disrupts the electrical activity of the nervous system, causing seizures. More than 65 million people in the world have epilepsy. 1 in 26 Americans will develop the disease during their lives. Children are the group most frequently diagnosed with new cases of epilepsy. In the United States, 300,000 children under 14 are affected by the condition. Some may outgrow the disorder, but most will not. The number of senior citizens with epilepsy is also 300,000. People with epilepsy have a range of treatment options, including alternative therapies. The illness is a complex condition, however, and all alternative treatment options must be looked at carefully, to ensure they are effective. Causes of epilepsy Epilepsy is a complex disease that can disrupt the electrical a...

Noninvasive Deep Brain Stimulation Can Become Reality, Mouse Study Shows

Researchers have, for the first time, showed that it is possible to stimulate structures deep within the brain without the need for implanted electrodes — opening the possibility that epilepsy patients could receive deep brain stimulation in a noninvasive manner. The method applies scalp electrodes that send two currents into the brain. Brain cells only become stimulated in the spot where the two currents intersect, making it possible to easily change the exact size and location of the treatment.

Secret of Epilepsy Discovered in Jerusalem?

Unable to figure out what causes the neurological disorder, the scientists thought to ask: What causes normal people (or lab animals) not to have it? Epileptic seizures are caused by abnormal activity in our brain. We know that. Attacks can be unprovoked or can be the result from a tendency that is created, for instance, by head trauma or exposure to certain stimuli. We know that too. We don’t know, however, is why some people are prone to epilepsy and some are not.

New Guideline Published on Uncommon Risk of Death in Epilepsy American Academy of Neurology

There is an uncommon risk of death that people with epilepsy and their loved ones may not know about. The risk is called sudden unexpected death in epilepsy, or SUDEP. Now the American Academy of Neurology (AAN) and the American Epilepsy Society have co-developed a new guideline on SUDEP, published in the April 24, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology, and presented at the 69th AAN Annual Meeting in Boston, April 22 to 28, 2017. The guideline is endorsed by the International Child Neurology Association. SUDEP is when someone with epilepsy who is otherwise healthy dies suddenly with no known cause.

The gene that turns epilepsy treatment deadly

Drug-induced hypersensitivity reactions (DIHRs) are serious and life threatening. A common example is the use of the antiepileptic drug carbamazepine, but the mechanisms that trigger it are unclear. Current scientific consensus holds that people who have a specific variation of the ‘human leukocyte antigen B’ (HLA-B) gene, which provides the code for making a protein that plays a critical role in the immune system, are more at risk of DIHR. However, the mechanism linking this gene to DIHR is currently unknown. As this specific variation, called HLA-B*15:02, is fairly common in people of South-East Asian descent, this is a serious problem for clinicians in the region.

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