Exposure to sodium valproate or a combination of antiepileptic drugs (AEDs) in utero is associated with worse attainment on national educational tests for 7-year-olds, according to a study published online March 26 in the Journal of Neurology, Neurosurgery & Psychiatry. Arron S. Lacey, from Swansea University Medical School in the United Kingdom, and colleagues identified children born to mothers with epilepsy and linked these children to their national attainment Key Stage 1 (KS1) tests in mathematics, language, and science at age 7. The children were compared with matched children born to mothers without epilepsy.
Prenatal folic acid supplements were found to reduce the risk of autistic traits in children born to women who were taking antiepileptic drugs while pregnant, according to a study published online on December 26 in JAMA Neurology. The risk was less for these women compared with those who did not take folic acid supplements.
The risk was higher when the mother took high doses of the drug than when she took lower doses. A study says a higher dose of topiramate drug during the first tri-semester of pregnancy may up the risk of cleft lip or cleft palate more than when taking a lower dose. Topiramate is prescribed to prevent seizures in people with epilepsy. It is also used to prevent migraine headaches or treat bipolar disorder. In combination with phentermine, it may be prescribed for weight loss. “While topiramate is not recommended for pregnant women, unplanned pregnancies are common, so it’s important to fully examine any possible risk,” said Sonia Hernandez-Diaz, from the Harvard T.H. Chan School of Public Health in Boston. Adding, “Our study found that when pregnant women took topiramate during the f...
Conclusion from a study of 1.4 million births. They are also three times as likely to develop the agonizing condition in later life Experts say children born to arthritis sufferers should be given ‘special attention’ The study, published in JAMA Pediatrics, was derived from 25 years of research
There is a significant relationship between the age of seizure onset and the age of menarche (the first occurrence of menstruation) in women with epilepsy, according to research presented at the 2017 American Epilepsy Society Annual Meeting, held December 1-5, 2017 in Washington, DC. Researchers gathered data from a web-based survey from the Epilepsy Birth Control Registry of 1144 women aged 18-47 who provided information on demographics, epilepsy diagnosis, antiepileptic drug use, and reproductive and contraceptive use.