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  1. Chemical chaperone: A new therapeutic option for epilepsy

    Chemical chaperone: A new therapeutic option for epilepsy

    Chemical chaperones correct the misfolding of the mutant protein Researchers found out that the conformational defect in a specific protein causes Autosomal Dominant Lateral Temporal Lobe Epilepsy (ADLTE) which is a form of familial epilepsy. They showed that treatment with chemical corrector called “chemical chaperone” ameliorates increased seizure susceptibility in...

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