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Breaching Blood-Brain Barrier Offers Safe And Noninvasive Drug Delivery For Alzheimer’s, Parkinson’s, ALS, Epilepsy And More

Columbia Engineering researchers have developed a new technique to reach neurons through the blood-brain barrier (BBB) and deliver drugs safely and noninvasively. Up until now, scientists have thought that long ultrasound pulses, which can inflict collateral damage, were required. But in this new study, the Columbia Engineering team show that extremely short pulses of ultrasound waves can open the...

How specific epilepsy treatments can limit seizures

Epilepsy is a neurological disorder, and according to the Centers for Disease Control, it afflicts at least 2 million Americans. While it’s not a disease in itself, it’s a manifestation of one of many different brain disorders. One of the common symptoms is recurring seizures. The options for treatment have increased dramatically over the past few decades for people living with epilepsy. One of th...

Teen turns epilepsy experience into a novel

Kelly Pretz admits she probably won the lottery of seizure disorders. “I’m very lucky,” said 15-year-old Kelly about her experiences with benign rolandic epilepsy. “The doctor said it’s the only type of epilepsy you can outgrow.” Still, being unexpectedly gripped in seizures that produce uncontrolled movements, sounds, excess saliva, pain and loss of consciousness can be frightening at...

Sudden Death in Epilepsy Plunges With Drug Treatment

Epilepsy patients with previously uncontrolled seizures have a much lower rate of sudden death if they are given adjunctive anti-epilepsy drugs, a meta-analysis has found. In an examination of 112 trials, the odds ratio for sudden unexpected death (SUDEP) in patients randomly assigned to anti-epileptic drugs (AEDs) at efficacious doses versus those assigned to placebo was 0.17 (95% CI 0.05 to 0.57...

The Cyborg in Us All

Platinum electrodes, used to record seizures, cover part of the brain in an epilepsy patient. Those electrodes collect electrical signals from the brain, some of which can be transformed into computer commands. “Fingers!” Gerwin Schalk sputtered, waving his hands around in the air. “Fingers are made to pick up a hammer.” He prodded the table, mimicking the way we poke at co...

Promising New Surgery For Epileptic Patients

More than 3-million Americans are affected by epilepsy. In about 40-percent of epileptic cases, drugs are unsuccessful and surgery is an option. Doctors at Texas Children’s Hospital have a new surgical technique that is simpler and less risky than a craniotomy. When 9 year old Keagan Dysart was just a baby, he would break into a giggle every now and then — even when nothing particularly funn...

New Device Reduces Seizures, No Surgery Required

Medications can cause mood problems, fatigue, or problems with thinking for some people. I see this as an alternative because it doesn’t cause those side effects. Christopher DeGiorgio, UCLA neurologist and inventor of the device.

Schizophrenia and epilepsy have ‘strong link’

People with schizophrenia are six times more likely to develop epilepsy, says a study which finds a strong relationship between the two diseases. Writing in Epilepsia, researchers in Taiwan say this could be due to genetic, neurobiological or environmental factors. The study followed around 16,000 patients with epilepsy and schizophrenia between 1999 and 2008. An epilepsy expert says it is an inte...

Can Seizure Meds Cause Acne?

If your doctor has put you on lithium or an anticonvulsant, be aware that an uncommon but possible side effect is acne. Certain drugs, including corticosteroids, lithium, anticonvulsants, barbiturates, androgenic steroids, DHEA, and medications that contain bromides or iodides, can cause true acne or acne-like eruptions. Lithium is prescribed for bipolar disorder. Some people take DHEA supplements...

What do medicines do for epilepsy? & Epilepsy: Taking your medicines properly.

You may be taking one or more medicines to prevent seizures. To get the most benefit from them, you need to consistently take the right dose of the right medicine at the right time. This can be difficult. But by following a few key tips, you can do it.

Dogs Detecting Seizures Before They Strike

It can happen at any time, any where, each year. Millions of Americans suffer seizures – caused when signals in the brain misfire. But now, new technology and man’s best friend may stop them before they start. It can happen at any time, any where, each year. Millions of Americans suffer seizures – caused when signals in the brain misfire. But now, new technology and man’s best friend may stop them...

Latest Perampanel Results Launch Approval Application

September 15, 2011 — The experimental epilepsy drug perampanel significantly reduced the frequency of partial-onset seizures as an adjunct therapy in treatment-resistant patients, according to the latest phase 3 results presented at the 2011 International Epilepsy Congress. With these results, the drug’s manufacturer, Eisai Inc, is submitting an application for US Food and Drug Administratio...