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Cannabis 101: A guide to CBD oil

Cannabidiol, or CBD, is a non-intoxicating chemical compound that comes from the cannabis sativa plant.  CBD is one of over 100 such compounds, known as cannabinoids, which are found in the plant. Unlike THC — or tetrahydrocannabinol, another cannabinoid — CBD is non-euphoric. What is the history of CBD? CBD was first discovered in the 1940’s by Roger Adams, the former head of the chemistry depart...

Epilepsy Epilepsy expert discusses latest research, side effects and FDA guidance for use aproved CBD treatment

Treating epilepsy presents a variety of challenges for patients and their families. Sometimes, it takes time to find the right medication and dosing to properly manage seizures and other epilepsy-related health issues. Or it may be necessary to adjust the medication so that it doesn’t cause side effects that impact quality of life. This is especially true for patients with two rare forms of severe...

Risk for Late-Onset Epilepsy Linked to a Class of Protein, Smoking, Diabetes

A recent study has shown that a class of proteins involved in the metabolism of fats in the body. Apolipoprotein E ε4 (APOE ε4) genotype and the presence of potentially modifiable risk factors such as smoking, hypertension, and diabetes in midlife are associated with a higher risk for late-onset epilepsy. Participants from the Atherosclerosis Risk in Communities (ARIC) study were enrolled in it. A...

Circadian and circaseptan rhythms in human epilepsy

Results of a recent study suggest that seizure cycles are robust, patient specific, and more widespread than previously understood. They align with the accepted consensus that most epilepsies have some diurnal influence. Variations in seizure rate have important clinical implications. Detection and tracking of seizure cycles on a patient-specific basis should be standard in epilepsy management pra...

LivaNova Launches Study to Assess VNS Therapy in Drug-resistant Epilepsy Patients

September 12, 2018:  LivaNova PLC announced the first implanted patient and official launch of a global registry to evaluate the use of LivaNova’s Vagus Nerve Stimulation Therapy® (VNS Therapy) System for patients with drug-resistant epilepsy (DRE), which affects nearly one in three people with epilepsy.1 The Comprehensive Outcomes Registry in Subjects with Epilepsy Treated with VNS Therapy (CORE-...

Federal chokehold on marijuana stymies studies on epilepsy, autism

A few years ago, I began to see children in my practice who seemingly responded to marijuana-derived extracts. And as a result, I grew cautiously optimistic that these extracts might be good treatments for the condition. As a devout believer in evidence-based medicine, I still needed experimental data that could distinguish bona fide effectiveness from a deceptive impression of benefit — a placebo...

Electronic device used to detect, treat epileptic seizures in mice

Researchers are hoping an electronic device used to detect, stop and prevent epileptic seizures in mice can be used to treat other neurological disorders, according to a study published in Science Advances. In the study led by a U.K. research team, scientists looked at the benefits of “direct in situ electrophoretic drug delivery to treat neurological disorders.” The team developed a neural probe ...

Ketogenic diet may help treat epilepsy by altering the gut microbiota

The ketogenic diet is known to successfully treat epilepsy for many people. In a recent study, researchers determine how the ketogenic diet alters the gut microbiota and if this mediates the anti-seizure effects. The ketogenic diet is a low-carbohydrate, high-fat diet that puts the body into a metabolic state called ketosis. During ketosis, the body is starved of carbohydrates and is forced to gen...

Dravet Syndrome Gene Mutation Linked to Sudden Unexpected Death in Epilepsy

Approximately half of Dravet syndrome patients experience the morbid outcome of sudden unexpected death in epilepsy (SUDEP). The causes behind SUDEP remain largely unknown, and there are no biomarkers that can be used to predict patients who are at increased risk. Now, investigators from Michigan Medicine have found that the high risk for SUDEP in patients with Dravet syndrome may be from a predis...

FUTURE – Brain implant could stop epilepsy seizures

For many people who suffer from neurological disorders, such as epilepsy, there are no viable treatment options. In our latest research, we developed an implantable device that may one day offer relief. We show that the implant can treat problems in the brain, such as epileptic seizures, by delivering brain chemicals – known as neurotransmitters – directly to the cells in the brain that cause the ...

Sudden Death Among Children with Epilepsy: 4x More Likely than Previously Thought

1.11 out of 1,000 children with epilepsy die suddenly each year, according to a Canadian study by CURE grantee Dr. Elizabeth Donner of the University of Toronto.1 Dr. Donner’s estimates confirm 2017 results garnered from the Swedish National Death Registry that also found the annual rate of sudden death to be 1.11 per 1,000 children with epilepsy.2 Both of these recent studies are in contrast to p...

Parental coping and its role in predicting health-related quality of life in pediatric epilepsy

Psychosocial difficulties are known to greatly impact the health-related quality of life of a child with epilepsy. Parental coping is a unique aspect of having a child with epilepsy that has not been examined in relation to health-related quality of life in the child with epilepsy until now. Parental coping with the condition is shown to be significantly related to the child’s health-related quali...