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Cannabis Derived Medicine

Yet More Good News for GW Pharma’s Cannabinoid Drug Against Epilepsy

Yet More Good News for GW Pharma’s Cannabinoid Drug Against Epilepsy

New data in The Lancet provides further support for GW Pharma’s drug, Epidiolex, for the treatment of a rare form of epilepsy.

 
GW Pharmaceuticals has achieved encouraging Phase III results for Epidiolex, which have been published in leading scientific journal, The Lancet. The company’s lead candidate is being developed for the treatment of epilepsy – a condition characterized by the abnormal firing of neurons in the brain, leading to seizures. In particular, the company targets Lennox-Gastaut syndrome, a rare, lifelong form of epilepsy, which causes significant developmental delays.


Over the 14-week treatment period, patients using Epidiolex suffered significantly fewer drop seizures than those using a placebo. This news is just one of the many signs pointing to the approval GW Pharma’s cannabinoid drug. In recent months, the company has also seen its new drug application approved by the FDA, received a cash injection of $276M (€235M), and been backed by Evaluate to join Genmab in the ‘blockbuster club’ by making sales of around $1B once its candidate makes it onto the market.

 

GW’s lead candidate, Epidiolex, is a liquid formulation of pure cannabidiol for severe early-onset, drug-resistant epilepsy. The exact mechanism of the drug is unknown but it has anti-convulsive effects in animal models, which may be facilitated by the reduced neuron excitability and transmission. With a lack of therapies approved specifically for Lennox-Gastaut syndrome, patients are often treated with drugs that have low efficacy but nasty side effects. For this reason, Epidiolex is also being developed for another difficult-to-treat form of epilepsy, Dravet syndrome.

Source: By A Dale for labiotech.eu

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1 Comment

  1. Our son is 27 yrs old and has had epilepsy since 15 yrs. His quality of life is very poor due to meds and Hodgkins Lymphoma treatments 2 yrs ago. We are very interested in this product.vwe live in SW Missouri. Please help.

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